Peric, Stojan (35750481700)Stojan (35750481700)PericBerisavac, Ivana (6507392420)Ivana (6507392420)BerisavacStojiljkovic Tamas, Olivera (57202112475)Olivera (57202112475)Stojiljkovic TamasRajic, Sonja (56516616500)Sonja (56516616500)RajicBabic, Milica (56516407400)Milica (56516407400)BabicCvijanovic, Milan (8208649800)Milan (8208649800)CvijanovicDominovic-Kovacevic, Aleksandra (37028225600)Aleksandra (37028225600)Dominovic-KovacevicBasta, Ivana (8274374200)Ivana (8274374200)BastaBeslac-Bumbasirevic, Ljiljana (6506489179)Ljiljana (6506489179)Beslac-BumbasirevicLavrnic, Dragana (6602473221)Dragana (6602473221)Lavrnic2025-06-122025-06-122016https://doi.org/10.1111/jns.12163https://www.scopus.com/inward/record.uri?eid=2-s2.0-85011344558&doi=10.1111%2fjns.12163&partnerID=40&md5=ccceda38712e5f5637ba48ab548f65c0https://remedy.med.bg.ac.rs/handle/123456789/7937The aim of the study was to analyze specific features of Guillain-Barré syndrome (GBS) in old people. The study included 403 GBS patients (62% young [<60 years], 35% young-old [60–80 years], and 3% old-old [>80 years]). Diagnosis of GBS was made according to the National Institute of Neurological Disorders and Stroke (NINDS criteria). Severe disability (GBS disability score of >3) at nadir was more common in old compared with young patients (p = 0.0001) as was mortality (9% vs. 2%, respectively). Acute motor and sensory axonal neuropathy and hyponatremia were more common in old compared with young patients (12% vs. 6% and 27% vs. 18%, respectively, p = 0.04). A positive history for malignancy was more than three times more common in old than young patients (11% vs. 3%, respectively, p = 0.01). Disability on nadir was similar in young-old and old-old subjects with disability on discharge being more severe in old-old (p = 0.04) suggesting slower recovery in this subgroup. Bulbar symptoms were more common in old-old compared with young-old (50% vs. 19%, respectively, p = 0.01). Comorbidities were present in virtually all old-old patients compared with 66% of young-old patients (p = 0.04). In conclusion, Elderly patients, and especially old-old patients, with GBS have more severe disease with slower recovery than do younger patients. © 2016 Peripheral Nerve SocietydiagnosisdisabilityelderlyGuillain-Barré syndrometherapy