Varagic, J. (6701708434)J. (6701708434)VaragicKoko, V. (26650963800)V. (26650963800)KokoTodorovic, V. (7006326762)V. (7006326762)TodorovicBozovic, Z. (57507508800)Z. (57507508800)BozovicLackovic, V. (35754725400)V. (35754725400)LackovicVuzevski, V. (7006382645)V. (7006382645)Vuzevski2025-06-122025-06-121996https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029912677&partnerID=40&md5=648aa648eae8d94fd9fe2468bb8d7acehttps://remedy.med.bg.ac.rs/handle/123456789/1614The effect of experimental protein malnutrition on gastrin producing cells in the antral part of the stomach was studied in male Wistar rats. Isoenergetic diets containing 25% (C-25) or 6% (PD-6) were given in isocaloric amounts during a 4-month experiment. All rats were offered drinking water ad libitum. The results showed that the long-term protein diet did not produce changes in the gastrin cell number. At the ultrastructural level G cells exhibited a decreased size of the nucleus. They were found to have an increased total granule volume density but the volume density of dense-cored granules was lower. The serum gastrin levels were significantly lowered by feeding the low protein diet. These changes are compatible with decreased functional activity of G cells under long-term protein deprivation.G cellhypoprotein nutritionmorphometryrat