Djokovic, A. (42661226500)A. (42661226500)DjokovicStojanovich, L. (55917563000)L. (55917563000)StojanovichStanisavljevic, N. (36163559700)N. (36163559700)StanisavljevicPopovic, M. (57197354363)M. (57197354363)PopovicZdravkovic, M. (24924016800)M. (24924016800)Zdravkovic2025-06-122025-06-122020https://doi.org/10.1177/0961203320906267https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079531845&doi=10.1177%2f0961203320906267&partnerID=40&md5=dc23a76c50a0956e87427276b302ca68https://remedy.med.bg.ac.rs/handle/123456789/4965Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a recently described, clinically significant entity, with prevalence rates ranging from 1% to 14% and a mean of 6% of all patients with myocardial infarction. Antiphospholipid syndrome (APS; Hughes syndrome) is characterized by the presence of antiphospholipid antibodies associated with thrombosis (arterial and/or venous) and/or pregnancy morbidity and could be the cause of MINOCA. Data on genetic predisposition to APS are scarce. The present study describes a unique case of monozygotic twin brothers who, at a young age, developed the same clinical presentation of APS. The diagnosis of APS was later confirmed, along with a diagnosis of systemic lupus erythematosus in one brother. © The Author(s) 2020.Antiphospholipid syndromeMINOCAsystemic lupus erythematosus