Bourne, Rupert R. A. (7103377631)Rupert R. A. (7103377631)BourneJonas, Jost B. (7202492953)Jost B. (7202492953)JonasFriedman, David (57221277002)David (57221277002)FriedmanNangia, Vinay (57201490837)Vinay (57201490837)NangiaBron, Alain (7103248039)Alain (7103248039)BronTapply, Ian (57205490881)Ian (57205490881)TapplyFernandes, Arthur G. (57192956381)Arthur G. (57192956381)FernandesCicinelli, Maria Vittoria (37260895200)Maria Vittoria (37260895200)CicinelliArrigo, Alessandro (56331647600)Alessandro (56331647600)ArrigoLeveziel, Nicolas (35321211600)Nicolas (35321211600)LevezielResnikoff, Serge (7006012071)Serge (7006012071)ResnikoffTaylor, Hugh R. (55550572900)Hugh R. (55550572900)TaylorSedighi, Tabassom (55368203500)Tabassom (55368203500)SedighiBikbov, Mukkharram M. (59156330300)Mukkharram M. (59156330300)BikbovBraithwaite, Tasanee (55522947000)Tasanee (55522947000)BraithwaiteCheng, Ching-Yu (55539712500)Ching-Yu (55539712500)ChengCongdon, Nathan (57217248626)Nathan (57217248626)CongdonDel Monte, Monte A. (7005134758)Monte A. (7005134758)Del MonteEhrlich, Joshua R. (57190136174)Joshua R. (57190136174)EhrlichFricke, Tim (7003797961)Tim (7003797961)FrickeFurtado, João M. (36801755000)João M. (36801755000)FurtadoGazzard, Gus (7004147260)Gus (7004147260)GazzardGeorge, Ronnie (7402637163)Ronnie (7402637163)GeorgeHartnett, M. Elizabeth (7005954310)M. Elizabeth (7005954310)HartnettKahloun, Rim (14119867400)Rim (14119867400)KahlounKempen, John H. (57216598048)John H. (57216598048)KempenKhairallah, Moncef (7004503022)Moncef (7004503022)KhairallahKhanna, Rohit C. (14060213400)Rohit C. (14060213400)KhannaKim, Judy E. (15026687500)Judy E. (15026687500)KimLansingh, Van Charles (57209471470)Van Charles (57209471470)LansinghLeasher, Janet (57220556967)Janet (57220556967)LeasherNaidoo, Kovin S. (35564549000)Kovin S. (35564549000)NaidooNowak, Michal (18437379100)Michal (18437379100)NowakPesudovs, Konrad (59156861800)Konrad (59156861800)PesudovsPeto, Tunde (7005772831)Tunde (7005772831)PetoRamulu, Pradeep (6602186935)Pradeep (6602186935)RamuluTopouzis, Fotis (57194262710)Fotis (57194262710)TopouzisTsilimbaris, Mitiadis (59324472200)Mitiadis (59324472200)TsilimbarisWang, Ya Xing (47962560100)Ya Xing (47962560100)WangWang, Ningli (7404340277)Ningli (7404340277)WangFlaxman, Seth (35190257400)Seth (35190257400)FlaxmanCasson, Robert James (6603840796)Robert James (6603840796)CassonFriedman, David S. (7402079597)David S. 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(59046499100)Marina G. (59046499100)BirckBitra, Veera R. (56394367200)Veera R. (56394367200)BitraBozic, Marija M. (26640219200)Marija M. (26640219200)BozicBurkart, Katrin (29067507300)Katrin (29067507300)BurkartBustanji, Yasser (8847282600)Yasser (8847282600)BustanjiButt, Zahid A. (57202522739)Zahid A. (57202522739)ButtCenderadewi, Muthia (57206668799)Muthia (57206668799)CenderadewiChattu, Vijay Kumar (55743746500)Vijay Kumar (55743746500)ChattuCoberly, Kaleb (58139389800)Kaleb (58139389800)CoberlyDadras, Omid (57205721978)Omid (57205721978)DadrasDai, Xiaochen (57221591169)Xiaochen (57221591169)DaiDascalu, Ana Maria (16038545200)Ana Maria (16038545200)DascaluDastiridou, Anna (35268364600)Anna (35268364600)DastiridouDevanbu, Vinoth Gnana Chellaiyan (55879226900)Vinoth Gnana Chellaiyan (55879226900)DevanbuDhimal, Meghnath (54941157300)Meghnath (54941157300)DhimalDiaz, Daniel (59614718400)Daniel (59614718400)DiazDo, Thao Huynh Phuong (58955491100)Thao Huynh Phuong (58955491100)DoDo, Thanh Chi (58537658400)Thanh Chi (58537658400)DoDziedzic, Arkadiusz Marian (56155198800)Arkadiusz Marian (56155198800)DziedzicEkholuenetale, Michael (57189344745)Michael (57189344745)EkholuenetaleElhadi, Muhammed (57212082248)Muhammed (57212082248)ElhadiEmamian, Mohammad Hassan (55181897800)Mohammad Hassan (55181897800)EmamianEmamverdi, Mehdi (57216906536)Mehdi (57216906536)EmamverdiFarrokhpour, Hossein (57210568865)Hossein (57210568865)FarrokhpourFetensa, Getahun (57211853863)Getahun (57211853863)FetensaFischer, Florian (55508208800)Florian (55508208800)FischerForouhari, Ali (57225200038)Ali (57225200038)ForouhariFowobaje, Kayode Raphael (57203988822)Kayode Raphael (57203988822)FowobajeGandhi, Aravind P. (57217858382)Aravind P. (57217858382)GandhiGebregergis, Miglas W. W. (58955738100)Miglas W. W. (58955738100)GebregergisGoulart, Bárbara Niegia Garcia (55958854600)Bárbara Niegia Garcia (55958854600)GoulartGudeta, Mesay Dechasa (58957214700)Mesay Dechasa (58957214700)GudetaGupta, Sapna (57217857409)Sapna (57217857409)GuptaGupta, Vivek Kumar (35073936800)Vivek Kumar (35073936800)GuptaGupta, Veer Bala (57194978364)Veer Bala (57194978364)GuptaHeidari, Golnaz (57218883864)Golnaz (57218883864)HeidariHong, Sung Hwi (57211663879)Sung Hwi (57211663879)HongHuynh, Hong-Han (58260528100)Hong-Han (58260528100)HuynhIbitoye, Segun Emmanuel (57212027408)Segun Emmanuel (57212027408)IbitoyeIlic, Irena M. (57210823522)Irena M. (57210823522)IlicImmurana, Mustapha (57215875071)Mustapha (57215875071)ImmuranaJayapal, Sathish Kumar (57202019648)Sathish Kumar (57202019648)JayapalJoseph, Nitin (35292547200)Nitin (35292547200)JosephJoshua, Charity Ehimwenma (58491197900)Charity Ehimwenma (58491197900)JoshuaKandel, Himal (57226834655)Himal (57226834655)KandelKaraye, Ibraheem M. (55598638900)Ibraheem M. (55598638900)KarayeKasraei, Hengameh (57194520224)Hengameh (57194520224)KasraeiKebebew, Getu Mosisa (57216873426)Getu Mosisa (57216873426)KebebewKhalafAlla, Mahmoud Tawfik (59324322400)Mahmoud Tawfik (59324322400)KhalafAllaKhanal, Sudarshan (57421947100)Sudarshan (57421947100)KhanalKhatib, Mahalaqua Nazli (25825057100)Mahalaqua Nazli (25825057100)KhatibKrishan, Kewal (57202279708)Kewal (57202279708)KrishanLahariya, Chandrakant (13205447400)Chandrakant (13205447400)LahariyaLim, Stephen S. (57201800433)Stephen S. (57201800433)LimMarzo, Roy Rillera (57163427600)Roy Rillera (57163427600)MarzoMaugeri, Andrea (56740683100)Andrea (56740683100)MaugeriMeng, Yang (59835907300)Yang (59835907300)MengMestrovic, Tomislav (6507240107)Tomislav (6507240107)MestrovicMishra, Manish (57213025989)Manish (57213025989)MishraMohamed, Nouh Saad (57208820453)Nouh Saad (57208820453)MohamedMojiri-forushani, Hoda (57200658736)Hoda (57200658736)Mojiri-forushaniMokdad, Ali H. (7004813962)Ali H. (7004813962)MokdadMomeni-Moghaddam, Hamed (54924501400)Hamed (54924501400)Momeni-MoghaddamMontazeri, Fateme (57924899400)Fateme (57924899400)MontazeriMulita, Admir (58491929200)Admir (58491929200)MulitaMurray, Christopher J. L. (57224556036)Christopher J. L. (57224556036)MurrayFoodani, Mahdi Nabi (57751110900)Mahdi Nabi (57751110900)FoodaniNaik, Ganesh R. (14825548600)Ganesh R. (14825548600)NaikNatto, Zuhair S. (37000768500)Zuhair S. (37000768500)NattoNayak, Biswa Prakash (56639942500)Biswa Prakash (56639942500)NayakNegaresh, Mohammad (57226439849)Mohammad (57226439849)NegareshNegash, Hadush (57209110507)Hadush (57209110507)NegashNguyen, Dang H. (57220970272)Dang H. (57220970272)NguyenOancea, Bogdan (26658614800)Bogdan (26658614800)OanceaOlagunju, Andrew T. (26029995700)Andrew T. (26029995700)OlagunjuOlatubi, Matthew Idowu (57200278115)Matthew Idowu (57200278115)OlatubiOsman, Wael M. S. (57195344402)Wael M. S. (57195344402)OsmanOsuagwu, Uchechukwu Levi (46062324800)Uchechukwu Levi (46062324800)OsuagwuPadubidri, Jagadish Rao (58295062300)Jagadish Rao (58295062300)PadubidriPardhan, Shahina (7003706887)Shahina (7003706887)PardhanPark, Seoyeon (57384211300)Seoyeon (57384211300)ParkPatel, Jay (59222700400)Jay (59222700400)PatelPerianayagam, Arokiasamy (15053062900)Arokiasamy (15053062900)PerianayagamPham, Hoang Tran (58627023500)Hoang Tran (58627023500)PhamPrates, Elton Junio Sady (58628448600)Elton Junio Sady (58628448600)PratesQattea, Ibrahim (57222260346)Ibrahim (57222260346)QatteaRahim, Fakher (23052247800)Fakher (23052247800)RahimRahman, Mosiur (55457953000)Mosiur (55457953000)RahmanRapaka, Deepthi (56394669700)Deepthi (56394669700)RapakaRawaf, Salman (6602475959)Salman (6602475959)RawafRezaei, Nazila (36700192900)Nazila (36700192900)RezaeiRoy, Priyanka (58956986100)Priyanka (58956986100)RoySaddik, Basema (23020079300)Basema (23020079300)SaddikSaeed, Umar (36612315100)Umar (36612315100)SaeedSafi, Sher Zaman (35620794800)Sher Zaman (35620794800)SafiSafi, Sare (57219477293)Sare (57219477293)SafiSakshaug, Joseph W. (35300521200)Joseph W. (35300521200)SakshaugSaleh, Mohamed A. (7201797507)Mohamed A. (7201797507)SalehSamuel, Vijaya Paul (12142874900)Vijaya Paul (12142874900)SamuelSamy, Abdallah M. (36973661300)Abdallah M. (36973661300)SamySaravanan, Aswini (58290959400)Aswini (58290959400)SaravananSeylani, Allen (57222325334)Allen (57222325334)SeylaniShaikh, Masood Ali (56673685600)Masood Ali (56673685600)ShaikhShamim, Muhammad Aaqib (58030336800)Muhammad Aaqib (58030336800)ShamimShannawaz, Mohammed (56349680200)Mohammed (56349680200)ShannawazShashamo, Bereket Beyene (57223025060)Bereket Beyene (57223025060)ShashamoShayan, Maryam (57209496707)Maryam (57209496707)ShayanShittu, Aminu (16418068900)Aminu (16418068900)ShittuSiddig, Emmanuel Edwar (55879555400)Emmanuel Edwar (55879555400)SiddigSingh, Jasvinder A. (58179112300)Jasvinder A. (58179112300)SinghSolomon, Yonatan (57220875005)Yonatan (57220875005)SolomonSousa, Raúl A. R. C. (57218215064)Raúl A. R. C. (57218215064)SousaTabatabaei, Seyyed Mohammad (55935372700)Seyyed Mohammad (55935372700)TabatabaeiTabish, Mohammad (57211184911)Mohammad (57211184911)TabishTicoalu, Jansje Henny Vera (57580368800)Jansje Henny Vera (57580368800)TicoaluToma, Temesgen Mohammed (59676110000)Temesgen Mohammed (59676110000)TomaTsatsakis, Aristidis (35596169100)Aristidis (35596169100)TsatsakisTsegay, Guesh Mebrahtom (57221594727)Guesh Mebrahtom (57221594727)TsegayValizadeh, Rohollah (57192641339)Rohollah (57192641339)ValizadehViskadourou, Maria (58822693600)Maria (58822693600)ViskadourouWassie, Gizachew Tadesse (57216988367)Gizachew Tadesse (57216988367)WassieWickramasinghe, Nuwan Darshana (55326938000)Nuwan Darshana (55326938000)WickramasingheYon, Dong Keon (57193675906)Dong Keon (57193675906)YonYou, Yuyi (49865138500)Yuyi (49865138500)YouSteinmetz, Jaimie D. (57221591053)Jaimie D. (57221591053)Steinmetz2025-06-122025-06-122024https://doi.org/10.1038/s41433-024-02995-5https://www.scopus.com/inward/record.uri?eid=2-s2.0-85199541563&doi=10.1038%2fs41433-024-02995-5&partnerID=40&md5=9839625a9af3a7278b32b94c07b7adbbhttps://remedy.med.bg.ac.rs/handle/123456789/958Objectives: To estimate global and regional trends from 2000 to 2020 of the number of persons visually impaired by glaucoma and their proportion of the total number of vision-impaired individuals. Methods: A systematic review and meta-analysis of published population studies and grey literature from 2000 to 2020 was carried out to estimate global and regional trends in number of people with vision loss due to glaucoma. Moderate or severe vision loss (MSVI) was defined as visual acuity of 6/60 or better but <6/18 (moderate) and visual acuity of 3/60 or better but <6/60 (severe vision loss). Blindness was defined as presenting visual acuity <3/60. Results: Globally, in 2020, 3.61 million people were blind and nearly 4.14 million were visually impaired by glaucoma. Glaucoma accounted for 8.39% (95% uncertainty intervals [UIs]: 6.54, 10.29) of all blindness and 1.41% (95% UI: 1.10, 1.75) of all MSVI. Regionally, the highest proportion of blindness relating to glaucoma was found in high-income countries (26.12% [95% UI: 20.72, 32.09]), while the region with the highest age-standardized prevalence of glaucoma-related blindness and MSVI was Sub-Saharan Africa. Between 2000 and 2020, global age-standardized prevalence of glaucoma-related blindness among adults ≥50 years decreased by 26.06% among males (95% UI: 25.87, 26.24), and by 21.75% among females (95% UI: 21.54, 21.96), while MSVI due to glaucoma increased by 3.7% among males (95% UI: 3.42, 3.98), and by 7.3% in females (95% UI: 7.01, 7.59). Conclusions: Within the last two decades, glaucoma has remained a major cause of blindness globally and regionally. © The Author(s) 2024.