Šipetić, Sandra (6701802171)Sandra (6701802171)ŠipetićVlajinac, Hristina (7006581450)Hristina (7006581450)VlajinacKocev, Nikola (6602672952)Nikola (6602672952)KocevBjekić, Milan (6602745387)Milan (6602745387)BjekićSajic, Silvija (24073590000)Silvija (24073590000)Sajic2025-06-132025-06-132005https://doi.org/10.1016/j.nut.2004.07.014https://www.scopus.com/inward/record.uri?eid=2-s2.0-16244380162&doi=10.1016%2fj.nut.2004.07.014&partnerID=40&md5=e59a7be4a3a23dd8a2b8e796bfc3dcbfhttps://remedy.med.bg.ac.rs/handle/123456789/11120Objectives: This study investigated whether an infant diet is associated with the development of type 1 diabetes. Methods: A case-control study was conducted in Belgrade from 1994 to 1997. A total of 105 patients with recent onset diabetes (≤16 y old) were compared with 210 controls chosen among children with skin disease (first control group). Cases and controls were individually matched by age (±1 y), sex, and place of residence. Eighty-six children with diabetes were also compared with their siblings (second control group). Results: According to univariate logistic regression analysis, when cases were compared with the first control group, the risk of type 1 diabetes was greater for children who were breast fed less than 4 mo (odds ratio = 2.09, 95% confidence interval = 1.30 to 3.36) and who received cow's milk at younger than 5 mo (odds ratio = 3.39, 95% confidence interval = 2.04 to 5.66). According to univariate analysis, when cases were compared with their relatives, only early introduction of supplementary milk was associated with a higher risk for diabetes (odds ratio = 5.75, 95% confidence interval = 2.91 to 11.36). After adjusting for different confounding variables, infant diet was not independently associated with diabetes. Conclusions: The results obtained do not support the hypothesis that infant diet is related to the occurrence of type 1 diabetes. © 2005 Elsevier Inc. All rights reserved.Breast fedCase-control studyChildhoodCow's milkDiabetes mellitus