Bozic Antic, Ivana (56016978300)Ivana (56016978300)Bozic AnticMacUt, Djuro (35557111400)Djuro (35557111400)MacUtPopovic, Bojana (36127992300)Bojana (36127992300)PopovicIsailovic, Tatjana (14421041700)Tatjana (14421041700)IsailovicPetakov, Milan (7003976693)Milan (7003976693)PetakovOgnjanovic, Sanja (14421284000)Sanja (14421284000)OgnjanovicDamjanovic, Svetozar (7003775804)Svetozar (7003775804)Damjanovic2025-07-022025-07-022014https://doi.org/10.3109/09513590.2013.864271https://www.scopus.com/inward/record.uri?eid=2-s2.0-84893139913&doi=10.3109%2f09513590.2013.864271&partnerID=40&md5=77e1a26e0428a5d91784e83b37603c52https://remedy.med.bg.ac.rs/handle/123456789/13732Introduction: Although numerous studies indicated a link between antithyroid antibodies and recurrent spontaneous abortions (RSA), consensus on the treatment of this condition is still lacking. Case report: We present a case of a 35-year-old pregnant woman (gestation week 4) with primary hypothyroidism, total alopecia, high level of positive antithyroid antibodies, and history of two recurrent spontaneous abortions in early pregnancy. Along with L-thyroxin substitution, intravenous human immunoglobulin (IVIg) combined with anticoagulation and antiaggregation therapy was introduced. During pregnancy her scalp hair completely re-grew, and following gestation week 39 she delivered healthy female child. Conclusion: Thyroid antibodies could contribute to previous recurrent abortions in our patient. It is suggested that in older primiparas with Hashimoto thyroiditis and history of RSA, a combined treatment with IVIg, anticoagulation and antiaggregation therapy should be considered. © 2014 Informa UK Ltd.Alopecia areataHashimoto thyroiditisHypothyroidismPregnancyRecurrent spontaneous abortions