Vujnic, Milorad (56079611800)Milorad (56079611800)VujnicPeric, Stojan (35750481700)Stojan (35750481700)PericPopovic, Srdjan (58426757200)Srdjan (58426757200)PopovicRaseta, Nela (37102638800)Nela (37102638800)RasetaRalic, Vesna (56047406400)Vesna (56047406400)RalicDobricic, Valerija (22952783800)Valerija (22952783800)DobricicNovakovic, Ivana (6603235567)Ivana (6603235567)NovakovicRakocevic-Stojanovic, Vidosava (6603893359)Vidosava (6603893359)Rakocevic-Stojanovic2025-06-122025-06-122015https://doi.org/10.1002/mus.24540https://www.scopus.com/inward/record.uri?eid=2-s2.0-84937520563&doi=10.1002%2fmus.24540&partnerID=40&md5=2d8e6d0cde4f960fb3a6477f37f0cec3https://remedy.med.bg.ac.rs/handle/123456789/8097Introduction: The aim of this study was to assess the frequency and features of metabolic syndrome (MetS) in myotonic dystrophy type 1 (DM1). Methods: We studied 66 DM1 patients (50% men, aged 41.9±10.5 years, disease duration of 19.3±8.6 years). New worldwide consensus criteria for MetS from 2009 were used. Results: Components of MetS were present at the following frequencies: hypertriglyceridemia 67%; low HDL cholesterol 35%; hypertension 18%; central obesity 14%; and hyperglycemia 9%. MetS was present in 11 (17%) patients. The presence of MetS was not associated with patients' gender, age, disease severity, disease duration, or CTG repeat length (P>0.05). Patients with MetS had significantly lower total SF-36 scores as a measure of quality of life in comparison to patients without MetS (P<0.05). Conclusion: Although certain components of MetS were very frequent in patients with DM1, only 17% met the criteria for MetS. © 2014 Wiley Periodicals, Inc.DyslipidemiaHypertensionMetabolic syndromeMyotonic dystrophy type 1Obesity