Stanojlovic, Svetlana (23502220700)Svetlana (23502220700)StanojlovicGlišic, Selimir (7005776789)Selimir (7005776789)GlišicArandjelovic, Snežana (19533573900)Snežana (19533573900)ArandjelovicKalezic, Tanja (55648169500)Tanja (55648169500)KalezicKrnjaja, Bojana Dacic (57196955455)Bojana Dacic (57196955455)KrnjajaSavic, Borivoje (51864509900)Borivoje (51864509900)Savic2025-06-122025-06-122021https://doi.org/10.2298/VSP181029013Shttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85101843825&doi=10.2298%2fVSP181029013S&partnerID=40&md5=8b34841d817a9b20b05189e3d52e6a6bhttps://remedy.med.bg.ac.rs/handle/123456789/4510Introduction. We report a rare case of cataract surgery in a patient with an extreme, widespread anterior staphyloma fol-lowing severe bilateral necrotising anterior scleritis associated with granulomatosis with polyangiitis (GPA). Case report. A 61-year-old man with a history of GPA developed bilateral, rapidly progressive necrotising scleritis and peripheral ulcera-tive keratitis (PUK). Inflammation compromised the entire anterior globe and peripheral cornea in both eyes. More than 90% of the surface area healed within 8 weeks, following the treatment with 3 pulsed doses of methylprednisolone in addi-tion to the cyclophosphamide treatment. Systemic steroid therapy was slowly tapered over a period of 6 months. Ex-traordinary scleral loss with a uveal bulge developed, follow-ing severe necrotising anterior scleritis associated with PUK. Once the full remission had been achieved after 6 months, uncomplicated phacoemulsification was performed in his left eye, the only functional one. Conclusion. Preoperative and postoperative control of inflammation, careful surgical plan-ning, and meticulous surgical techniques are critically im-portant for optimal surgical outcome in such patients. To our knowledge, phacoemulsification in a patient with coexisting uveitic cataract and severe anterior staphyloma has not been previously reported. © 2021 Inst. Sci. inf., Univ. Defence in Belgrade. All rights reserved.Cataract extractionCorneal ulcerGranulomatosis with polyangiitisScleritisTreatment outcome