Martic, Vesna (6602650915)Vesna (6602650915)MarticBozovic, Ivo (57194468421)Ivo (57194468421)BozovicBerisavac, Ivana (6507392420)Ivana (6507392420)BerisavacBasta, Ivana (8274374200)Ivana (8274374200)BastaPeric, Stojan (35750481700)Stojan (35750481700)PericBabic, Milica (56516407400)Milica (56516407400)BabicRajic, Sonja Lukic (56516616500)Sonja Lukic (56516616500)RajicBjelica, Bogdan (57194461405)Bogdan (57194461405)BjelicaTamas, Olivera Stojiljkovic (57202112475)Olivera Stojiljkovic (57202112475)TamasStojanov, Aleksandar (57194143903)Aleksandar (57194143903)StojanovGrunauer, Marija (57202112783)Marija (57202112783)GrunauerCobeljic, Mina (57196349878)Mina (57196349878)CobeljicKomatina, Nenad (56516845100)Nenad (56516845100)KomatinaDjuric, Vanja (35361619800)Vanja (35361619800)DjuricPetrovic, Milutin (36969833200)Milutin (36969833200)PetrovicVujovic, Balsa (57021631300)Balsa (57021631300)VujovicKovacevic, Aleksandra Dominovic (59577737900)Aleksandra Dominovic (59577737900)KovacevicDjordjevic, Gordana (35763715800)Gordana (35763715800)DjordjevicJovanovic, Dejana (55419203900)Dejana (55419203900)JovanovicStevic, Zorica (57204495472)Zorica (57204495472)Stevic2025-07-022025-07-022018https://doi.org/10.1017/cjn.2018.12https://www.scopus.com/inward/record.uri?eid=2-s2.0-85047192915&doi=10.1017%2fcjn.2018.12&partnerID=40&md5=9df6e154b6d251ccc3e865501c3f082dhttps://remedy.med.bg.ac.rs/handle/123456789/12964A majority of patients with Guillain-Barré syndrome (GBS) have tendency of a good recovery. Our aim was to evaluate the outcome of the disease 1 and 3 years after GBS symptom onset. Methods: During 2014, GBS was diagnosed in 82 patients in seven tertiary healthcare centers. Neurological follow-up was conducted in 57 (70%) patients after 1 year, and in 54 (66%) after 3 years. Functional disability was estimated according to the GBS disability scale (GDS), with a score of 0-3 indicating mild disability and a score of 4-6 indicating severe disability during acute phase, whereas a score >1 indicated poor recovery on follow-ups. Visual analog scale was used to assess sensory symptoms and musculoskelatal pain, and Krupp's Fatigue Severity Scale was used to asses fatigue. Results: Poor functional outcome was found in 39% of GBS patients at year 1 and 30% at year 3. Paresthesias/dysesthesias were detected in 60% of patients after 1 year and 43% after 3 years. Musculoskeletal pain was present in 40% of patients at year 1 and 33% at year 3. Significant fatigue after 1 year was found in 21% of subjects and after 3 years in 7%. Parameters associated with poor functional outcome after 1 year were age >55 years (p=0.05), severe disability at admission (p<0.05), and on discharge (p<0.01). Poor functional outcome after 3 years was associated with male gender (p<0.05) and severe disability on discharge (p=0.06). Conclusion: One and even three years after GBS onset, a substantial number of patients had neurological sequelae, including functional disability, sensory symptoms, pain, and fatigue. © 2018 The Canadian Journal of Neurological Sciences Inc.FatigueFunctional disabilityGuillain-Barré syndromePainProspective study