Gayden, Tenzin (16068625100)Tenzin (16068625100)GaydenBukhari, Areej (36174013700)Areej (36174013700)BukhariChennakrishnaiah, Shilpa (35486853700)Shilpa (35486853700)ChennakrishnaiahStojkovic, Oliver (35618950700)Oliver (35618950700)StojkovicHerrera, Rene J. (7103233331)Rene J. (7103233331)Herrera2025-06-122025-06-122012https://doi.org/10.1016/j.fsigen.2011.09.002https://www.scopus.com/inward/record.uri?eid=2-s2.0-84861332988&doi=10.1016%2fj.fsigen.2011.09.002&partnerID=40&md5=74c139054a8b2097abad39677ad2b6a8https://remedy.med.bg.ac.rs/handle/123456789/9799In the present study, we analyzed 17 Y-STR loci in 350 Tibetan males from three culturally defined regions of historical Tibet: Amdo (88), Kham (109) and U-Tsang (153). A total of 299 haplotypes were observed, 272 (90.9%) of which were unique. Only one Y-STR profile is shared across the three Tibetan groups and, incidentally, is also the most frequent haplotype (4.0%), represented by two, five and seven individuals from U-Tsang, Kham and Amdo, respectively. The overall haplotype diversity for the three Tibetan populations at 17 Y-STR loci was 0.9978 and the corresponding values for the extended (11-loci) and minimal (9-loci) haplotypes were 0.9935 and 0.9909, respectively. Both neighbor-joining and Rst pairwise analyses suggest a close genetic relationship between the Amdo and Kham populations, while U-Tsang is genetically distinct from the aforementioned groups. The results demonstrate that the 17 Y-STR loci analyzed are highly polymorphic in all three Tibetan populations examined and hence useful for forensic cases, paternity testing and population genetic studies. © 2011 Elsevier Ireland Ltd.AmdoKhamTibetU-TsangY-STRYfiler