Petrović, Milorad (55989504900)Milorad (55989504900)PetrovićJanković, Z. (56216490800)Z. (56216490800)JankovićJauković, Lj. (12769289900)Lj. (12769289900)JaukovićArtiko, Vera (55887737000)Vera (55887737000)ArtikoŠobic-Šaranovic, Dragana (57202567582)Dragana (57202567582)Šobic-ŠaranovicAntić, Andrija (6603457520)Andrija (6603457520)AntićŽuvela, Marinko (6602952252)Marinko (6602952252)ŽuvelaRadovanović, Nebojša (57221820776)Nebojša (57221820776)RadovanovićPalibrk, Ivan (6507415211)Ivan (6507415211)PalibrkGalun, Danijel (23496063400)Danijel (23496063400)GalunMatić, Slavko (7004660212)Slavko (7004660212)MatićLončar, Zlatibor (26426476500)Zlatibor (26426476500)LončarBojović, Predrag (29367568800)Predrag (29367568800)BojovićAjdinovic, Boris (24167888800)Boris (24167888800)AjdinovicObradovic, Vladimir (7003389726)Vladimir (7003389726)Obradovic2025-06-122025-06-122013https://doi.org/10.5754/hge121035https://www.scopus.com/inward/record.uri?eid=2-s2.0-84885792912&doi=10.5754%2fhge121035&partnerID=40&md5=bb0e0e281ceee6835786f8df848f5467https://remedy.med.bg.ac.rs/handle/123456789/8988Background/Aim: The aim of this study was to evaluate the clinical reliability of the immunoscintigraphy with radiolabeled monoclonal antibodies for the detection of metastases and recurrences of rectal carcinomas. Methodology: A total of 65 patients underwent immunoscintigraphy with radiolabeled monoclonal antibodies. Indication for that examination was suspicious rectal cancer or suspicious rectal cancer recurrence and/or metastases. Results: The method proved to have 92.7% sensitivity, specificity 83.3%, positive predictive value 90.5%, negative predictive value 87.0% and accuracy 89.2%. There was a statistically significant relationship between immunoscintigraphy findings and rectoscopy findings (rs=0.415, p=0.013), as well as significant relationship between immunoscintigraphy findings and US findings (rs=0.332, p=0.001). Tumor marker levels were in positive correlation with findings of immunoscintigraphy (r s=0.845, p=0.001), especially raised CEA level (rs=0.816, p=0.004). Patients with higher CA19-9 level had higher Duke's stage (p=0.025). Conclusions: We can conclude that immunoscintigraphy can be helpful in the detection of metastases and recurrences of colon carcinomas. © H.G.E. Update Medical Publishing S.A.I-131ImmunoscintigraphyMonoclonal antibodiesRectal carcinoma