Milovanovic, Tamara (55695651200)Tamara (55695651200)MilovanovicPantic, Ivana (57223613349)Ivana (57223613349)PanticDragasevic, Sanja (56505490700)Sanja (56505490700)DragasevicLugonja, Sofija (57219557462)Sofija (57219557462)LugonjaDumic, Igor (57200701725)Igor (57200701725)DumicRajilic-Stojanovic, Mirjana (16319789000)Mirjana (16319789000)Rajilic-Stojanovic2025-06-122025-06-122021https://doi.org/10.15403/jgld-3308https://www.scopus.com/inward/record.uri?eid=2-s2.0-85105911179&doi=10.15403%2fjgld-3308&partnerID=40&md5=ed2d082b19d3b5374568714fd47b7603https://remedy.med.bg.ac.rs/handle/123456789/4494Non-alcoholic fatty liver disease and colonic diverticulosis are widespread, obesity-related diseases. It has recently become clear that non-alcoholic fatty liver disease is a systemic disease and may play a key role in metabolic syndrome; therefore, the term metabolic-dysfunction-associated fatty liver disease has been introduced in the literature. Excess visceral adipose tissue is an important predictor of complications in both non-alcoholic fatty liver disease and colonic diverticulosis. Current evidence suggests that intestinal dysbiosis may be involved in the development of both non-alcoholic fatty liver disease and colonic diverticulosis, and that metabolic syndrome is a consequence rather than a cause of this complex relationship. In this review, our aim was to assess the current knowledge of the complex interplay between metabolic syndrome, non-alcoholic fatty liver disease, and colonic diverticulosis. © 2021, Romanian Society of Gastroenterology. All rights reserved.DiverticulosisMetabolic syndromeMetabolic-dysfunction-associated fatty liver diseaseNon-alcoholic fatty liver disease