Jovanovic, Valentina Balint (59693905800)Valentina Balint (59693905800)JovanovicFarkic, Mihajlo (56725607400)Mihajlo (56725607400)FarkicBoljevic, Darko (57204930789)Darko (57204930789)BoljevicBojic, Milovan (7005865489)Milovan (7005865489)BojicFurtula, Matija (58161992800)Matija (58161992800)FurtulaTopic, Dragan (24330141400)Dragan (24330141400)TopicDobric, Milan (23484928600)Milan (23484928600)DobricIelasi, Alfonso (14520490200)Alfonso (14520490200)IelasiZobenica, Vladimir (58118595100)Vladimir (58118595100)ZobenicaSubotic, Ida (57213608856)Ida (57213608856)SuboticNikolic, Aleksandra (59432908700)Aleksandra (59432908700)Nikolic2025-06-122025-06-122025https://doi.org/10.14740/cr1751https://www.scopus.com/inward/record.uri?eid=2-s2.0-105000052773&doi=10.14740%2fcr1751&partnerID=40&md5=5f4b89d09c8aa3849a47414992c92e63https://remedy.med.bg.ac.rs/handle/123456789/683The natural progression of bioprosthetic valve degeneration over time requires further interventions for those experiencing symptomatic prosthesis dysfunction. Transcatheter aortic valve replacement (TAVR) emerges as a promising therapeutic option to alleviate symptoms in such patients. The valve-in-valve (ViV) technique eliminates the necessity for repetitive open-heart surgical procedures, offering particular advantages for individuals with higher surgical risks. In this report, we describe the case of a 78-year-old female patient presenting with severe symptomatic aortic restenosis of a biological aortic valve implanted 5 years prior. Given the patient’s high surgical risk, a transcatheter ViV implantation was chosen as the treatment approach. Utilizing a balloon-expandable valve, the intervention resulted in the successful implantation of a functional TAVR, resulting in symptom relief and enabling a fast discharge from the hospital. © The authorsAortic restenosisBalloon-expandable valveFailed surgical bioprosthesesMyval OctacorTranscatheter aortic valve replacementTranscatheter heart valveValve-in-valve