Maksimović, R.M. (55921156500)R.M. (55921156500)MaksimovićDunjić, M S Kratovac (6602366154)M S Kratovac (6602366154)DunjićLilić, G.B. (8239856400)G.B. (8239856400)LilićMilenković, R.M. (24478937300)R.M. (24478937300)MilenkovićMasulović, D.M. (57215645003)D.M. (57215645003)MasulovićMilićević, M. (57510647400)M. (57510647400)Milićević2025-06-122025-06-122009https://doi.org/10.2298/ACI0904121Mhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-77952342116&doi=10.2298%2fACI0904121M&partnerID=40&md5=540ec7cfa258db8e35cadb094f1dd757https://remedy.med.bg.ac.rs/handle/123456789/10591INTRODUCTION: The study was designed to determine if there was a difference between apparent diffusion coefficient (ADC) values using diffusion weighted imaging (DWI) MRI technique between different malignant focal liver lesions. PATIENTS AND METHODS: The study included 63 patients with focal hepatic lesions: fourteen patients (22.2%) with hepatocellular carcinoma (HCC), 16 patients (25.4%) with hepatic metastatic colorectal tumors, 17 patients (26.9%) with cavernous haemangioma and 16 patients (25.4%) with hepatic cysts. MRI was performed with 1.5T scanner, using EPI sequence with ADC values being determined for all lesions based on three b values. RESULTS: ADC values were statistically different among the groups (F = 70.7, p < 0.01): HCC patients 1.11 +/- 0.29 x 10(-3) s/mm2, metastatic tumours 2.18 +/- 0.15 x 10(-3) s/mm2, haemangioma 2.22 +/- 0.32 x 10(-3) s/mm, cysts 3.08 +/- 0.03 x 10(-3) s/mm2. Furthermore, there was statistically significant difference between benign lesions (haemangiom and cysts, 2.36 +/- 0.43 x 10(-3) s/mm2), and malignant diseases (HCC and secondary tumors, 1.52 +/- 0.58 x 10(-3) s/mm2), t = 5,6, p < 0.01.CONCLUSION: DWI technique could be helpful in defining the focal liver lesions.