Lalosevic, Jovan (57190969635)Jovan (57190969635)LalosevicGajic-Veljic, Mirjana (24767639800)Mirjana (24767639800)Gajic-VeljicNikolic, Milos (56910382000)Milos (56910382000)Nikolic2025-06-122025-06-122017https://doi.org/10.1111/pde.13279https://www.scopus.com/inward/record.uri?eid=2-s2.0-85033793157&doi=10.1111%2fpde.13279&partnerID=40&md5=a58ffa98f5b5fe315aaa393334ca758bhttps://remedy.med.bg.ac.rs/handle/123456789/6701Orofacial granulomatosis, a rare disease in childhood, is characterized by orofacial swelling in the absence of systemic disease. We report the case of a 12-year-old girl with asymptomatic erythematous infiltration of her upper lip, cheeks, and chin that had persisted for more than 2 years; biopsy confirmed granuloma formation. Because a large area was affected, intralesional corticosteroids were inappropriate and six cycles of 3-day intravenous pulse corticosteroid therapy (dexamethasone 1.5mg/kg), repeated once after 4 weeks, was given. Our patient also received oral chloroquine and topical emollients. At the end of the sixth pulse cycle, the infiltration had completely resolved, leaving slight residual erythema. © 2017 Wiley Periodicals, Inc.chloroquineMelkersson-Rosenthal syndromeorofacial granulomatosispulse corticosteroid therapy