Mihailovic-Vucinic, Violeta (13410407800)Violeta (13410407800)Mihailovic-VucinicJovanovic, Dragana (58721901700)Dragana (58721901700)Jovanovic2025-06-122025-06-122008https://doi.org/10.1016/j.ccm.2008.03.002https://www.scopus.com/inward/record.uri?eid=2-s2.0-44649107773&doi=10.1016%2fj.ccm.2008.03.002&partnerID=40&md5=23353f5fd047f471e38c2312495cfa4chttps://remedy.med.bg.ac.rs/handle/123456789/10742Sarcoidosis is an inflammatory granulomatous disease that is characterized by diverse organ system manifestations, a variable clinical course, and a predilection for affecting relatively young adults worldwide. Abnormalities on chest radiographs are detected in 85% to 95% of patients who have sarcoidosis. Approximately 20% to 50% of patients who have sarcoidosis present with respiratory symptoms, including dyspnea, cough, chest pain, and tightness of the chest. The clinical course and manifestations of pulmonary sarcoidosis are protean: spontaneous remission occurs in approximately two thirds of patients; up to 30% of patients have chronic course of the lung disease, resulting in progressive, (sometimes life-threatening) loss of lung function. Morbidity that correlates to sarcoidosis occurs in 1% to 4% of patients. © 2008 Elsevier Inc. All rights reserved.