Ilic, Vesna (58717187600)Vesna (58717187600)IlicNikitovic, Marina (6602665617)Marina (6602665617)NikitovicMaric, Gorica (56433592800)Gorica (56433592800)MaricJovanovic, Aleksa (57216047949)Aleksa (57216047949)JovanovicParipovic, Lejla (55342754900)Lejla (55342754900)ParipovicBokun, Jelena (6507641875)Jelena (6507641875)BokunStanic, Dragana (56941616400)Dragana (56941616400)StanicVukovic, Marija Popovic (57203171901)Marija Popovic (57203171901)VukovicTepavcevic, Darija Kisic (57218390033)Darija Kisic (57218390033)TepavcevicPekmezovic, Tatjana (7003989932)Tatjana (7003989932)Pekmezovic2025-06-122025-06-122020https://doi.org/10.1007/s00520-020-05348-6https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079452462&doi=10.1007%2fs00520-020-05348-6&partnerID=40&md5=dba48a71906abab248e252fb2e653810https://remedy.med.bg.ac.rs/handle/123456789/4704Purpose: The aim of the study was to assess health-related quality of life (HRQoL) and contributing factors among parents of children with solid tumors in Serbia. Methods: The cross-sectional study included 51 parents of children treated for different solid tumors at the Institute of Oncology and Radiology of Serbia. Parents filled out validated Serbian version of SF-36 questionnaire. Hierarchical multiple regression analysis was conducted to identify predictors of total score of SF-36. Results: Almost all parents (94.1%) were mothers and average age was 38.6 ± 6.7 years. Majority of children had brain tumors (43.1%), followed by bone tumors (37.3%). The hierarchical regression analysis showed that socio-demographic characteristics explained 26% of the variance (p > 0.05) of the total score of SF-36. Addition of quality of life of children assessed by parents in the second model caused an increase of 21% in the variance explained (p < 0.05). After adding the Beck Depression Inventory score in the third block, an additional 18% of the variance in total score was explained (p < 0.05). Conclusions: This study showed that HRQoL measured by SF-36 in parents of children with cancer is strongly influenced by depression and quality of life of children assessed by parents. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.Childhood cancerHealth-related quality of lifeHierarchical regression analysisParents