Salević, Petar (56469660900)Petar (56469660900)SalevićRadović, Pavle (56469431600)Pavle (56469431600)RadovićMilić, Nataša (7003460927)Nataša (7003460927)MilićBogdanović, Radovan (7004665744)Radovan (7004665744)BogdanovićParipović, Dušan (14621764400)Dušan (14621764400)ParipovićParipović, Aleksandra (35311948800)Aleksandra (35311948800)ParipovićGolubović, Emilija (6602901479)Emilija (6602901479)GolubovićMilosević, Biljana (22981084000)Biljana (22981084000)MilosevićMulić, Bilsana (56469655800)Bilsana (56469655800)MulićPeco-Antić, Amira (7004525216)Amira (7004525216)Peco-Antić2025-06-122025-06-122014https://doi.org/10.1007/s40620-014-0094-8https://www.scopus.com/inward/record.uri?eid=2-s2.0-84920475408&doi=10.1007%2fs40620-014-0094-8&partnerID=40&md5=d0072c6cfbb9b2608372ac529989ac39https://remedy.med.bg.ac.rs/handle/123456789/8504Background: Growth retardation is one of the most visible comorbid conditions of chronic kidney disease (CKD) in children. To our knowledge, published data on longitudinal follow-up of growth in pediatric patients with CKD is lacking from the region of South-East Europe. Herein we report the results from the Serbian Pediatric Registry of Chronic Kidney Disease.; Methods: The data reported in the present prospective analysis were collected between 2000 and 2012. A total of 324 children with CKD were enrolled in the registry.; Results: Prevalence of growth failure at registry entry was 29.3 %. Mean height standard deviation scores (HtSDS) in children with stunting and those with normal stature were −3.00 [95 % confidence interval (CI) −3.21 to −2.79] and −0.08 (95 % CI −0.22 to 0.05) (p < 0.001), respectively. Children with hereditary nephropathy had worse growth at registration (−1.51; 95 % CI −1.97 to −1.04, p = 0.008). Those with CKD stages 4 and 5 before registration had more chance to have short stature at registration than those with CKD stages 2 and 3 [odds ratio (OR) = 0.458, CI 0.268–0.782, p = 0.004]. Dialysis was an independent negative predictor for maintaining optimal stature during the follow-up period (OR = 0.324, CI = 0.199–0.529, p < 0.001), while transplantation was an independent positive predictor for improvement of small stature during follow-up (OR = 3.706, CI = 1.785–7.696, p < 0.001).; Conclusion: Growth failure remains a significant problem in children with CKD, being worst in patients with hereditary renal disease. Growth is not improved by standard dialysis, but transplantation has a positive impact on growth in children. © 2014, Italian Society of Nephrology.ChildrenChronic kidney diseaseDialysisGrowth failureTransplantation