Lalić, Nebojša M. (13702597500)Nebojša M. (13702597500)LalićLalić, Katarina (13702563300)Katarina (13702563300)LalićJotić, Aleksandra (13702545200)Aleksandra (13702545200)JotićStanojević, Dejan (55596857900)Dejan (55596857900)StanojevićŽivojinović, Dragana (36555120400)Dragana (36555120400)ŽivojinovićJanićijević, Andrija (57194834507)Andrija (57194834507)JanićijevićParkin, Christopher (13411311500)Christopher (13411311500)Parkin2025-06-122025-06-122017https://doi.org/10.1177/1932296816681323https://www.scopus.com/inward/record.uri?eid=2-s2.0-85023157832&doi=10.1177%2f1932296816681323&partnerID=40&md5=dc0c700d48c29f76df8a46400fc7f15bhttps://remedy.med.bg.ac.rs/handle/123456789/6943Background: We assessed the effect of structured self-monitoring of blood glucose (SMBG), in combination with intensive education, on metabolic control, SMBG frequency, hospitalizations, cardiovascular risk factors, and quality-of-life parameters in patients with insulin-treated diabetes in primary health care settings in Serbia. Methods: This 6-month, observational, noninterventional study, followed 346 insulin-treated diabetes patients (type 1 diabetes [T1D], n = 57; type 2 diabetes [T2D], n = 289) from 28 primary care centers. Patients attended a 10-day course at the specialized educational center and were followed monthly by their primary care physicians. Patients used a simple paper tool to document 3-day, 7-point glucose profiles prior to each monthly clinic visit. Physicians reviewed the completed forms at each visit and used a standardized education program to provide remedial training. Changes in HbA1c levels, SMBG frequency, metabolic risk factors, and Diabetes Distress Scale (DDS) were assessed. Results: Mean (± SD) HbA1c within the full cohort was significantly improved from baseline at 6 months (8.85 ± 1.17% vs 7.91 ± 1.24%, P <.01). Significant increases in average SMBG frequency per week were seen at 6 months versus baseline (14.6/week vs 4.3/week, P <.001). The mean (± SE) number of hospitalizations due to metabolic conditions was significantly lower during the 6-month study compared to the 6-month period prior to the study (0.14 ± 0.04 vs 0.59 ± 0.09). DDS scores decreased from 39.6 ± 13.9 to 33.9 ± 14.5, P <.01. Conclusion: The use of structured SMBG combined with intensive education was associated with clinically significant reductions in HbA1c, increased SMBG frequency, and improved quality of life. © Diabetes Technology Society.HbA1cstructured SMBGtype 1 diabetestype 2 diabetesThe Impact of Structured Self-Monitoring of Blood Glucose Combined with Intensive Education on HbA1c Levels, Hospitalizations, and Quality-of-Life Parameters in Insulin-Treated Patients with Diabetes at Primary Care in Serbia: The Multicenter SPA-EDU Study