Petrović, Jovan (57315862300)Jovan (57315862300)PetrovićŠvabić, Tamara (54783513300)Tamara (54783513300)ŠvabićZidverc-Trajković, Jasna (18134546100)Jasna (18134546100)Zidverc-TrajkovićStanarčević, Predrag (55353773400)Predrag (55353773400)StanarčevićJovanović, Dejana (55419203900)Dejana (55419203900)JovanovićMijajlović, Milija (55404306300)Milija (55404306300)Mijajlović2025-06-122025-06-122022https://doi.org/10.1007/s10072-021-05514-6https://www.scopus.com/inward/record.uri?eid=2-s2.0-85111730605&doi=10.1007%2fs10072-021-05514-6&partnerID=40&md5=fae5e76c5d0a7d650a6efbd14c1af4edhttps://remedy.med.bg.ac.rs/handle/123456789/3590Thrombosis of dural sinuses and/or cerebral veins (CVT) is an uncommon form of stroke, usually affecting young individuals. It has a variable clinical presentation ranging from mild cases presenting only headaches, to severe cases featuring encephalopathy, coma or status epilepticus. A retrospective cross-sectional study of patients treated in the outpatient department and in-hospital during the period from 2014 to 2020 at the Neurology Clinic—University Clinical Centre of Serbia was conducted. Forty-nine patients (24 men; 25 women) were included in the study. Twenty-three patients (46.9%) suffered a subacute form of CVT (48 h—4 weeks), 19 (38.8%) presented with an acute form (< 48 h) and 7 (14.3%) with a chronic form (> 4 weeks). Around 75% of patients reported headaches during disease course. Focal neurological deficit (FND) was observed in 27 (55.1%) patients. Patients who did not report headaches (22.4%) presented with more severe symptoms (seizures and coma). More than 70% of patients had no radiologically evident brain parenchymal lesion. The most frequent locations of CVT were transverse sinus (79.6%), sigmoid sinus (44.9%) and superior sagittal sinus (36.7%). Thrombosis of more than one sinus/vein occurred in 33 (67.3%) patients. Hereditary thrombophilia was observed in 9 (18.4%) patients, 11 (22.4%) patients had some type of infection and 20% of women reported OCT usage. As much as 25% of cases remained without evident risk factors. The most common symptom in our cohort was acute unilateral throbbing headache of high intensity, while patients without headaches had more severe symptoms. © 2021, Fondazione Società Italiana di Neurologia.Cerebral venous thrombosisClinical presentationHeadacheNeuroimagingRisk factors