Zivaljevic, Vladan (6701787012)Vladan (6701787012)ZivaljevicVlajinac, Hristina (7006581450)Hristina (7006581450)VlajinacMarinkovic, Jelena (7004611210)Jelena (7004611210)MarinkovicPaunovic, Ivan (55990696700)Ivan (55990696700)PaunovicDiklic, Aleksandar (6601959320)Aleksandar (6601959320)DiklicDzodic, Radan (6602410321)Radan (6602410321)Dzodic2025-07-022025-07-022004https://doi.org/10.1177/030089160409000301https://www.scopus.com/inward/record.uri?eid=2-s2.0-3242801400&doi=10.1177%2f030089160409000301&partnerID=40&md5=5a1e82b3aa0e7b366b557d5cbc2f52e4https://remedy.med.bg.ac.rs/handle/123456789/14457Aims and background: Thyroid cancer, whose etiology is largely uncertain, has been negatively associated with cigarette smoking in a several studies. We examined the association between cigarette smoking and risk for female thyroid cancer. Methods: A case-control study including 204 histologically verified female thyroid cancer patients and an equal number of hospital controls individually matched with cases by sex, age (± 2 years), place of residence and time of hospitalization was carried out during the period 1996-2000. In the analysis of data, univariate and multivariate conditional logistic regression methods were applied. Results: According to univariate analysis, female thyroid cancer was negatively associated with the initiation of smoking at a younger age, before the age of 20 (OR = 0.66, 95% CI = 0.50-0.90). None of the smoking habits remained independently related to female thyroid cancer after adjustment for other factors which were significantly associated with thyroid cancer in the present study. Conclusions: The results of the study do not suggest a role of cigarette smoking in the development of thyroid cancer in women.Case-control studyCigarette smokingFemaleThyroid cancer