Single prognostic cut-off value for admission glycemia in acute myocardial infarction has been used although high-risk stems from hyperglycemia as well as from hypoglycemia (a narrative review)

Koraćević, Goran (24341050000)Goran (24341050000)KoraćevićMićić, Slađana (57212551841)Slađana (57212551841)MićićStojanović, Milovan (57188923072)Milovan (57188923072)StojanovićTomašević, Miloje (57196948758)Miloje (57196948758)TomaševićKostić, Tomislav (26023450500)Tomislav (26023450500)KostićKoraćević, Maja (36188111200)Maja (36188111200)KoraćevićJanković, Irena (35848631200)Irena (35848631200)Janković2025-06-122025-06-122020https://doi.org/10.1016/j.pcd.2020.09.004https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091711311&doi=10.1016%2fj.pcd.2020.09.004&partnerID=40&md5=1c17afbc51f552d1a8843ab0dd7d0c1bhttps://remedy.med.bg.ac.rs/handle/123456789/4592All original articles and meta-analysis use the single cut-off value to distinguish high-risk hyperglycemic from other acute myocardial infarction (AMI) patients. The mortality rate is 3.9 times higher in non-diabetic AMI patients with admission glycemia ≥6.1 mmol compared to normoglycemic non-diabetic AMI patients. On the other hand, admission hypoglycemia in AMI is an important predictor of mortality. Because both admission hypo- and hyperglycemia correspond to higher in-hospital mortality, this graph is recognized as “J or U shaped curve”. The review suggests two cut-off values for admission glycemia for risk assessment in AMI instead of single one because hypoglycemia as well as hyperglycemia represents a high-risk factor. © 2020 Primary Care Diabetes EuropeAcute myocardial infarctionCut-off valueHyperglycemiaHypoglycemiaSingle prognostic cut-off value for admission glycemia in acute myocardial infarction has been used although high-risk stems from hyperglycemia as well as from hypoglycemia (a narrative review)