Ilić, Irena (57210823522)Irena (57210823522)IlićŠipetić, Sandra (6701802171)Sandra (6701802171)ŠipetićGrujičić, Jovan (57212211501)Jovan (57212211501)GrujičićMačužić, Ivana Živanović (23570133700)Ivana Živanović (23570133700)MačužićKocić, Sanja (34880317700)Sanja (34880317700)KocićIlić, Milena (7102981394)Milena (7102981394)Ilić2025-06-122025-06-122019https://doi.org/10.3390/medicina55120772https://www.scopus.com/inward/record.uri?eid=2-s2.0-85076213465&doi=10.3390%2fmedicina55120772&partnerID=40&md5=a8d46ec6e41d742ef2c1fd1e9a5fea6chttps://remedy.med.bg.ac.rs/handle/123456789/5337Background and Objectives: Studies on the effects of studying on a medical student’s quality of life are sparse. The World Health Organization Quality of Life (WHOQOL-BREF) questionnaire is a widely used scale that enables the assessment and international comparisons of the quality of life. The aim of this study was to evaluate psychometric properties of the WHOQOL-BREF questionnaire among Serbian medical students. Material and Methods: We conducted a crosssectional study that involved 760 medical students at a state medical faculty at the University of Kragujevac, Serbia. The reliability of the WHOQOL-BREF was evaluated using Cronbach’s alpha coefficient and test–retest analysis, and the validity was examined using principal component analysis, with Promax rotation method. Results: Cronbach’s alpha coefficient for the whole WHOQOL-BREF scale was 0.896. Internal reliability for all domains was above 0.70, except for the domain “Social Relationships” (0.533). The test–retest reliability for all domains was significant at p < 0.01 level, showing good stability of the scale. Principal component analysis with Promax rotation method indicated four main components that explained 49.5% of variance. Conclusion: The Serbian version of the WHOQOL-BREF scale showed satisfactory psychometric properties that facilitate estimation of the quality of life of medical students. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.Medical studentsQuality of lifeReliabilityValidityWHOQOL-BREF