Antunovic, Tanja (55322578700)Tanja (55322578700)AntunovicStefanovic, Aleksandra (15021458500)Aleksandra (15021458500)StefanovicRatkovic, Marina (6603579593)Marina (6603579593)RatkovicGledovic, Branka (55322422100)Branka (55322422100)GledovicGligorovic-Barhanovic, Najdana (55322483000)Najdana (55322483000)Gligorovic-BarhanovicBozovic, Dragica (55322263100)Dragica (55322263100)BozovicIvanisevic, Jasmina (54389258300)Jasmina (54389258300)IvanisevicProstran, Milica (7004009031)Milica (7004009031)ProstranStojanov, Marina (6601955965)Marina (6601955965)Stojanov2025-06-122025-06-122013https://doi.org/10.1007/s11255-012-0233-xhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84881478190&doi=10.1007%2fs11255-012-0233-x&partnerID=40&md5=eace3c1b4caf6f99ed972a8bb530a6e0https://remedy.med.bg.ac.rs/handle/123456789/8971Purpose: We investigated the role of serum uric acid (sUA) and superoxide dismutase (SOD) as predictive factors for mortality in hemodialysis (HD) patients. Methods: SOD, butyrylcholinesterase, and malondialdehyde were estimated spectrophotometrically and the other parameters by standard procedures. High-sensitive C-reactive protein was assayed by a sandwich ELISA method. Results: sUA among survivors (112.1 ± 13.82 μmol/L) was significantly lower than in deceased (160.8 ± 16.81 μmol/L, p < 0.001), while SOD was higher in survivors (31.8 ± 6.61 kU/L) than among deceased (20.2 ± 3.03, p < 0.05). Kaplan-Meier survival curves showed the greatest mortality risk in the highest tertile of basal sUA concentration (≥127.11 μmol/L, p < 0.001), and for SOD in the lowest tertile (≤23.83 kU/L, p < 0.05). Conclusion: Our results suggest that high sUA and low SOD may predict all-cause and cardiovascular mortality in HD patients. © 2012 Springer Science+Business Media, B.V.Cardiovascular risk mortalityHemodialysisSuperoxide dismutaseUric acid