Radenkovic, Sandra (36615697100)Sandra (36615697100)RadenkovicKonjevic, Gordana (56008692300)Gordana (56008692300)KonjevicIsakovic, Aleksandra (57202555421)Aleksandra (57202555421)IsakovicStevanovic, Predrag (24315050600)Predrag (24315050600)StevanovicGopcevic, Kristina (14035482300)Kristina (14035482300)GopcevicJurisic, Vladimir (6603015144)Vladimir (6603015144)Jurisic2025-06-122025-06-122014https://doi.org/10.1093/rpd/ncu243https://www.scopus.com/inward/record.uri?eid=2-s2.0-84922418084&doi=10.1093%2frpd%2fncu243&partnerID=40&md5=f08c39b34efed195398b978e0d2b7c3ehttps://remedy.med.bg.ac.rs/handle/123456789/8511Human epidermal growth factor receptor 2 (HER2)-positive breast cancers represent a highly aggressive breast cancer subtype and are associated with a worse prognosis. This study was designed to investigate the mammography finding of HER2-positive breast cancer and to compare the results with the characteristics of HER2-negative breast cancer patients. From January 2010 to October 2011, mammography findings of 65 patients with pathologically confirmed HER2-positive breast cancers (n 5 22) or HER2-negative breast cancers (n 5 43) were retrospectively reviewed. The authors also reviewed pathological reports for information on the histological type and differentiation grade. Among the two types of breast cancer patients, estrogen receptornegative/PR-negative/HER2-positive breast cancer patients most commonly had associated calcifications (18 of 22) on mammography. On mammography, cases with a cluster of calcifications usually were presented as pleomorphic calcifications (12 of 20) and branching calcifications (4 of 20). Patients with HER2-positive breast cancers showed a histological grade II. HER2-positive breast cancer patients usually had ductal invasive carcinoma (17 of 22). Moreover, postmenopausal patients showed a significantly higher frequency of HER2-positive tumours. Our results suggest that the imaging findings might be useful in diagnosing HER2-positive breast cancer patients. © The Author 2014.