Stajer, Valdemar (57191498986)Valdemar (57191498986)StajerTrivic, Tatjana (39262410600)Tatjana (39262410600)TrivicDrid, Patrik (57209794562)Patrik (57209794562)DridVranes, Milan (16246559800)Milan (16246559800)VranesOstojic, Sergej M. (8552029600)Sergej M. (8552029600)Ostojic2025-06-122025-06-122016https://doi.org/10.1139/apnm-2016-0102https://www.scopus.com/inward/record.uri?eid=2-s2.0-84991105236&doi=10.1139%2fapnm-2016-0102&partnerID=40&md5=10fa1bbf5389d2bea8da4c3c0083bc0dhttps://remedy.med.bg.ac.rs/handle/123456789/7934We evaluated the effects of exercise on circulating concentrations of guanidinoacetic acid (GAA) and creatine in 23 healthy volunteers subjected to running to exhaustion and free-weight bench-press to volitional failure. Blood was taken before and following each exercise session. Running induced a significant decrease in serum GAA by 20.1% (P < 0.001), while free-weight exercise reduced GAA by 11.7% (P < 0.001), suggesting the possible use of serum GAA as a novel biomarker of exhaustion. © 2016, Canadian Science Publishing. All rights reserved.Bench pressBioenergeticsCreatineCreatinineRunning-to-exhaustion