Hobart, Jeremy (7005144498)Jeremy (7005144498)HobartBowen, Amy (56415911300)Amy (56415911300)BowenPepper, George (55790374900)George (55790374900)PepperCrofts, Harriet (57205492874)Harriet (57205492874)CroftsEberhard, Lucy (57205484973)Lucy (57205484973)EberhardBerger, Thomas (7202632707)Thomas (7202632707)BergerBoyko, Alexey (7102247663)Alexey (7102247663)BoykoBoz, Cavit (6701728553)Cavit (6701728553)BozButzkueven, Helmut (57201788612)Helmut (57201788612)ButzkuevenCelius, Elisabeth Gulowsen (6601956387)Elisabeth Gulowsen (6601956387)CeliusDrulovic, Jelena (55886929900)Jelena (55886929900)DrulovicFlores, José (16156497400)José (16156497400)FloresHoráková, Dana (55053678000)Dana (55053678000)HorákováLebrun-Frénay, Christine (57217110407)Christine (57217110407)Lebrun-FrénayMarrie, Ruth Ann (56962754600)Ruth Ann (56962754600)MarrieOverell, James (6603320145)James (6603320145)OverellPiehl, Fredrik (7004836264)Fredrik (7004836264)PiehlRasmussen, Peter Vestergaard (57197895341)Peter Vestergaard (57197895341)RasmussenSá, Maria José (7003714039)Maria José (7003714039)Sîrbu, Carmen-Adella (34975964800)Carmen-Adella (34975964800)SîrbuSkromne, Eli (14030672500)Eli (14030672500)SkromneTorkildsen, Øivind (8714244300)Øivind (8714244300)Torkildsenvan Pesch, Vincent (15847200900)Vincent (15847200900)van PeschVollmer, Timothy (7006075665)Timothy (7006075665)VollmerZakaria, Magd (55340059600)Magd (55340059600)ZakariaZiemssen, Tjalf (6602879721)Tjalf (6602879721)ZiemssenGiovannoni, Gavin (34770127900)Gavin (34770127900)Giovannoni2025-07-022025-07-022019https://doi.org/10.1177/1352458518809326https://www.scopus.com/inward/record.uri?eid=2-s2.0-85060242807&doi=10.1177%2f1352458518809326&partnerID=40&md5=25401cca1fe76440f9cccb657f4e6c11https://remedy.med.bg.ac.rs/handle/123456789/12634Background: Time matters in multiple sclerosis (MS). Irreversible neural damage and cell loss occur from disease onset. The MS community has endorsed a management strategy of prompt diagnosis, timely intervention and regular proactive monitoring of treatment effectiveness and disease activity to improve outcomes in people with MS. Objectives: We sought to develop internationally applicable quality standards for timely, brain health–focused MS care. Methods: A panel of MS specialist neurologists participated in an iterative, online, modified Delphi process to define ‘core’, ‘achievable’ and ‘aspirational’ time frames reflecting minimum, good and high care standards, respectively. A multidisciplinary Reviewing Group (MS nurses, people with MS, allied healthcare professionals) provided insights ensuring recommendations reflected perspectives from multiple stakeholders. Results: Twenty-one MS neurologists from 19 countries reached consensus on most core (25/27), achievable (25/27) and aspirational (22/27) time frames at the end of five rounds. Agreed standards cover six aspects of the care pathway: symptom onset, referral and diagnosis, treatment decisions, lifestyle, disease monitoring and managing new symptoms. Conclusion: These quality standards for core, achievable and aspirational care provide MS teams with a three-level framework for service evaluation, benchmarking and improvement. They have the potential to produce a profound change in the care of people with MS. © The Author(s), 2018.benchmarkingconsensusDelphi techniqueMultiple sclerosisquality improvementstandardsInternational consensus on quality standards for brain health-focused care in multiple sclerosis