Stojanović, Marina (7004959142)Marina (7004959142)StojanovićKalezić, Nevena (6602526969)Nevena (6602526969)KalezićMiličić, Biljana (6603829143)Biljana (6603829143)MiličićTošković, Anka (56609235500)Anka (56609235500)ToškovićStevanović, Ksenija (57376155800)Ksenija (57376155800)StevanovićAntonijević, Vesna (57224641487)Vesna (57224641487)AntonijevićLakićević, Mirko (12647605400)Mirko (12647605400)LakićevićBagi, Bojan (57202392974)Bojan (57202392974)BagiŽivaljević, Vladan (6701787012)Vladan (6701787012)Živaljević2025-06-122025-06-122018https://doi.org/10.2298/SARH170522156Shttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85048150835&doi=10.2298%2fSARH170522156S&partnerID=40&md5=3f2f9253e55320bb20601c56bbd1d931https://remedy.med.bg.ac.rs/handle/123456789/6589Introduction/Objective Intraoperative variations in blood pressure and/or cardiac dysrhythmias (IOVBP/CD) represent one of the most common causes of morbidity and mortality in surgical patients. The aim of the study was to determine the incidence and risk factors for IOVBP/CD in thyroid surgery patients with comorbidities. Methods The study included 1,252 euthyroid patients with ASA 2 and ASA 3 status (American Society of Anesthesiologists – physical status classification) who underwent thyroid surgery. The following risk factors were examined: sex, age, body mass index (BMI), ASA status, admission diagnoses, type of operation, duration of surgery, time under general anesthesia, difficult intubation of trachea, and coexisting diseases – hypertension, cardiomyopathy, cardiac arrhythmias, angina pectoris, diabetes mellitus, kidney disease. The following intraoperative events were recorded: hypertension, severe hypertension, hypotension, and cardiac arrhythmias. We used Pearson χ2 square test, univariate, and multivariate logistic regression for statistical analysis. Results The majority of patients were female (86.3%). In 903 (72.1%) patients IOVBP/CD were detected. The most common problem was intraoperative hypertension (61.4%). Eight risk factors for IOVBP/CD were registered by univariate analysis: advanced age, ASA 3 status, BMI > 25 kg/m², duration of surgery, time under general anesthesia, hypertension, and cardiomyopathy as a coexisting disease. The multivariate regression model identified three independent predictors for IOVBP/CD: age, hypertension, and cardiomyopathy. Conclusion IOVBP/CD are common in thyroid surgery. The most common is intraoperative hypertension. Older age, hypertension, and cardiomyopathy as a coexisting disease are independent risk factors for IOVBP/CD. © 2018, Serbia Medical Society. All rights reserved.Arrhythmias, cardiacHypertensionHypotensionThyroidectomy