Kalezić, Nevena (6602526969)Nevena (6602526969)KalezićKaradžić-Kočica, Milica (57221724942)Milica (57221724942)Karadžić-KočicaDimić, Nemanja (57460624900)Nemanja (57460624900)DimićKočica, Mladen J. (6507502534)Mladen J. (6507502534)KočicaTošković, Anka (56609235500)Anka (56609235500)ToškovićJovanović, Milan (57210477379)Milan (57210477379)JovanovićDimitrijević, Ivan (57207504419)Ivan (57207504419)Dimitrijević2025-06-122025-06-122021https://doi.org/10.2298/SARH201123113Khttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85143836920&doi=10.2298%2fSARH201123113K&partnerID=40&md5=a5725726f5780b4693ecf1d1b545216bhttps://remedy.med.bg.ac.rs/handle/123456789/4313Introduction/Objective Alcohol abuse influence on developing thyroid cancer is controversial. While some studies consider it a protective factor, others deny any impact on thyroid cancer. The objective of the paper was to establish a possible link between alcohol abuse and certain types of thyroid cancers. Methods The retrospective study included 502 patients with thyroid cancer and a control group of 600 patients with benign forms of thyroid diseases (e.g. nodular, multinodular, and toxic nodular goiter). Thyroid cancer patients were divided into four groups: I – papillary, II – medullary, III – anaplastic, and IV – follicular carcinoma, and grouped by sex, age (< 30 years; > 30 years) and alcohol abuse, as defined by the World Health Organization. Results Thyroid cancer patients were predominantly male of younger age. This distribution difference was statistically significant in groups I and II (p < 0.001). Of total 10 (0.9%) patients with chronic alcohol abuse, eight (1.6%) had thyroid cancer, while two (0.3%) belonged to the control group (p < 0.001). In thyroid cancer patients, chronic alcohol abuse was absent from groups III and IV. Distribution in groups I and II was six (1.6%) and two (2%), respectively (p < 0.001). Conclusion Alcohol abuse deserves to be considered as a risk factor for papillary and medullary forms of thyroid cancer, while it does not stay the same for anaplastic and follicular thyroid cancers. © 2021, Serbia Medical Society. All rights reserved.alcohol abuseanaplastic cancerfollicular cancermedullary cancerpapillary cancerthyroid cancer