Muraru, Denisa (57203383206)Denisa (57203383206)MuraruPontone, Gianluca (8342393600)Gianluca (8342393600)PontoneJurcut, Ruxandra (25228919600)Ruxandra (25228919600)JurcutMagne, Julien (22938314200)Julien (22938314200)MagneDonal, Erwan (7003337454)Erwan (7003337454)DonalStankovic, Ivan (57197589922)Ivan (57197589922)StankovicAnagnostopoulos, Constantinos (55400597100)Constantinos (55400597100)AnagnostopoulosBartko, Philipp E. (36631572100)Philipp E. (36631572100)BartkoBijnens, Bart (7005275311)Bart (7005275311)BijnensFontana, Marianna (16306839900)Marianna (16306839900)FontanaGalli, Elena (59573629400)Elena (59573629400)GalliMichalski, Blazej (14527627100)Blazej (14527627100)MichalskiMarra, Martina Perazzolo (9235712600)Martina Perazzolo (9235712600)MarraPezel, Théo (57204933661)Théo (57204933661)PezelRossi, Alexia (36183503300)Alexia (36183503300)RossiSmiseth, Otto A. (7006367337)Otto A. (7006367337)SmisethVan de Veire, Nico (9437143300)Nico (9437143300)Van de VeireEdvardsen, Thor (6603263370)Thor (6603263370)EdvardsenPetersen, Steffen E. (35430477200)Steffen E. (35430477200)PetersenCosyns, Bernard (57202595662)Bernard (57202595662)Cosyns2025-06-122025-06-122025https://doi.org/10.1093/ehjci/jeae238https://www.scopus.com/inward/record.uri?eid=2-s2.0-85214318377&doi=10.1093%2fehjci%2fjeae238&partnerID=40&md5=969c8b3fc0172b5060554c61a95d421bhttps://remedy.med.bg.ac.rs/handle/123456789/695This statement from the European Association of Cardiovascular Imaging (EACVI) of the ESC aims to address the fundamental principles that guide clinical research in the field of cardiovascular imaging. It provides clinical researchers, cardiology fellows, and PhD students with a condensed, updated, and practical reference document to support them in designing, implementing, and conducting imaging protocols for clinical trials. Although the present article cannot replace formal research training and mentoring, it is recommended reading for any professional interested in becoming acquainted with or participating in clinical trials involving cardiovascular imaging. © The Author(s) 2024.cardiovascular imagingclinical trialsresearchresearch methodologystudy designHow to conduct clinical research in cardiovascular imaging: a primer for clinical cardiologists and researchers—a statement of the European Association of Cardiovascular Imaging (EACVI) of the ESC