Krstic, Miodrag (35341982900)Miodrag (35341982900)KrsticAlempijevic, Tamara (15126707900)Tamara (15126707900)AlempijevicStimec, Bojan (7003411337)Bojan (7003411337)StimecMicev, Marjan (7003864533)Marjan (7003864533)MicevMilicevic, Miroslav (7005565664)Miroslav (7005565664)MilicevicMicic, Dragan (7006038410)Dragan (7006038410)MicicJankovic, Goran (7005387171)Goran (7005387171)Jankovic2025-06-132025-06-132007https://doi.org/10.3748/wjg.v13.i22.3144https://www.scopus.com/inward/record.uri?eid=2-s2.0-34447283038&doi=10.3748%2fwjg.v13.i22.3144&partnerID=40&md5=67b8fc2d1fda822bb3d72bd6ad61b4d3https://remedy.med.bg.ac.rs/handle/123456789/10851Villous adenomas are benign epithelial lesions with malignant potential that can occur in any part of the gastrointestinal tract. We present a case of a middle age woman with acromegaly who was investigated for nonspecific gastrointestinal complaints. Ultrasonography and subsequent endosonography diagnosed a large (4.5 cm), hyperechoic, sessile polyp with numerous pedicles. An open cholecystectomy was performed and revealed a villous adenoma with several foci of carcinoma in situ. Detailed investigations showed no other tumors of the gastrointestinal tract. After five years of follow-up, the patient reports no complaints, and the results of laboratory testing and imaging studies are within the normal range. © 2007 The WJG Press. All rights reserved.AcromegalyEndosonographyGallbladderVillous adenoma