Blagojevic, Nikola R. (57219697551)Nikola R. (57219697551)BlagojevicBosnjakovic, Dragana (57219705604)Dragana (57219705604)BosnjakovicVukomanovic, Vladan (57144261800)Vladan (57144261800)VukomanovicArsenovic, Srdjan (57219697786)Srdjan (57219697786)ArsenovicLazic, Jelena Suzic (37023567700)Jelena Suzic (37023567700)LazicTadic, Marijana (36455305000)Marijana (36455305000)Tadic2025-06-122025-06-122020https://doi.org/10.1016/j.ijid.2020.09.1440https://www.scopus.com/inward/record.uri?eid=2-s2.0-85094854252&doi=10.1016%2fj.ijid.2020.09.1440&partnerID=40&md5=5bb068341ad2ac30db553d49bb76d7e0https://remedy.med.bg.ac.rs/handle/123456789/4627We present the case of a 51-year-old patient with acute pericarditis as the dominant manifestation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patient was admitted to the emergency department during a coronavirus disease 2019 (COVID-19) outbreak with a suspected ST-elevation myocardial infarction. A coronary angiogram was normal. Real-time reverse transcriptase PCR for the detection of nucleic acid from SARS-CoV-2 in a nasopharyngeal swab was positive. Laboratory tests revealed an increased white blood cell count, with neutrophilia and lymphocytopenia, elevated level of C-reactive protein, borderline elevated erythrocyte sedimentation rate, and slightly elevated interleukin 6. Echocardiography showed a hyperechogenic pericardium posterolaterally with minimal localized pericardial effusion. A chest computed tomography scan showed a small zone of ground-glass opacity in the right lower lobe (classified as CO-RADS 3). In patients with chest pain, ST elevation on electrocardiogram, a normal coronary angiogram, and suspected COVID-19, we should think of pericarditis as an unusual presentation of SARS-CoV-2 infection. © 2020 The Author(s)COVID-19PericarditisSARS-CoV-2