Vratonjic, Jelena (57216883910)Jelena (57216883910)VratonjicJovanovic, Ivana (57223117334)Ivana (57223117334)JovanovicPetrovic, Olga (33467955000)Olga (33467955000)PetrovicPaunovic, Ivana (57197090935)Ivana (57197090935)PaunovicBoricic-Kostic, Marija (36191774200)Marija (36191774200)Boricic-KosticTesic, Milorad (36197477200)Milorad (36197477200)TesicNedeljkovic-Arsenovic, Olga (57191857920)Olga (57191857920)Nedeljkovic-ArsenovicMaksimovic, Ruzica (55921156500)Ruzica (55921156500)MaksimovicIvanovic, Branislava (24169010000)Branislava (24169010000)IvanovicTrifunovic-Zamaklar, Danijela (9241771000)Danijela (9241771000)Trifunovic-Zamaklar2025-06-122025-06-122022https://doi.org/10.1002/jcu.23335https://www.scopus.com/inward/record.uri?eid=2-s2.0-85139463333&doi=10.1002%2fjcu.23335&partnerID=40&md5=55929ca8708b1d0c6b8d2d79ae2c3739https://remedy.med.bg.ac.rs/handle/123456789/3272Advanced cardiac imaging (ACI), including myocardial deformation imaging, 3D echocardiography and cardiac magnetic resonance, overcomes the limitations of conventional echocardiography in the assessment of patients with primary mitral regurgitation (MR). They enable a more precise MR quantification and reveal early changes before advanced and irreversible remodeling with depressed heart function occurs. ACI permits a thorough analysis of mitral valvular anatomy and MR mechanisms (important for planning and guiding percutaneous and surgical procedures) and helps to identify structural and functional changes coupled with a high arrhythmogenic potential, especially the occurrence of atrial fibrillation and heart failure development. The key question is how the data provided by ACI can improve the current management of primary MR. © 2022 Wiley Periodicals LLC.cardiac magnetic resonancemitral valve prolapsemyocardial deformation imagingprimary MR