Tomanovic, Marija (58092757700)Marija (58092757700)TomanovicReljic, Vesna (55895308600)Vesna (55895308600)ReljicPeric, Jelena (55894863200)Jelena (55894863200)PericZivanovic, Dubravka (24170307900)Dubravka (24170307900)Zivanovic2025-06-122025-06-122023https://doi.org/10.3855/jidc.18040https://www.scopus.com/inward/record.uri?eid=2-s2.0-85179608003&doi=10.3855%2fjidc.18040&partnerID=40&md5=996196cf16543d0f3e34bfb292522effhttps://remedy.med.bg.ac.rs/handle/123456789/2489Introduction: This brief picture-oriented case report focuses on typical skin lesions in a patient who developed Ecthyma gangrenosum and pseudomonal sepsis after extensive immunosuppressive therapy for Pemphigus vulgaris. Case presentation: The patient was immunosuppressed with high doses of glucocorticoids and azathioprine; the follow-up after the treatment was not carried out well due to the pandemic conditions and because the patient herself got a Covid infection, which resulted in the development of pseudomonal sepsis and Ecthyma gangrenosum. The outcome was fatal despite extensive broad-spectrum antibiotic therapy, plasmapheresis, and intravenous immunoglobulins. Conclusions: Infections with Pseudomonas aeruginosa have become a real concern in hospital-acquired infections, especially in critically ill and immunocompromised patients, because of multi-drug resistance in the first place. Copyright © 2023 Tomanovic et al.Ecthyma gangrenosumimmunocompromisedPemphigus vulgarisPseudomonas aeruginosasepsis