Sipetic, S. (6701802171)S. (6701802171)SipeticMaksimovic, J. (23567176900)J. (23567176900)MaksimovicVlajinac, H. (7006581450)H. (7006581450)VlajinacRatkov, I. (55957120100)I. (55957120100)RatkovSajic, S. (24073590000)S. (24073590000)SajicZdravkovic, D. (7004544358)D. (7004544358)ZdravkovicSipetic, T. (47761763700)T. (47761763700)Sipetic2025-06-122025-06-122013https://doi.org/10.3275/8619https://www.scopus.com/inward/record.uri?eid=2-s2.0-84879007080&doi=10.3275%2f8619&partnerID=40&md5=f12b0d2cc5072c0867268b021d06917ahttps://remedy.med.bg.ac.rs/handle/123456789/9119Background: Type 1 diabetes (T1DM) is an autoimmune disease in which both genetic and environmental factors play a role in the etiology. Aim: The aim of this studywas to analyze the incidence of T1DM. Methods: A retrospective technique was used to register all newly diagnosed cases of T1DM in Belgrade (Serbia) children at the age of 0-14 yr between 1982 and 2005. The incidence was adjusted directly by age using the Segi's world population as the standard. A total of 702 cases was identified from the two sources: patients' records from two pediatric hospitals in Belgrade referent for the disease, and from the population based register. Results: The average annual age adjusted incidence rate of T1DM for Belgrade was 10.4/100,000 [95% confidence interval (95% CI)=3.8-15.4]. It was slightly higher in boys than in girls. The age-specific annual incidence rates (per 100,000) for the age groups 0-4, 5-9, and 10-14were 5.5 (95% CI=4.5-6.7), 11.9 (95% CI=10.5-13.5), and 15.4 (95% CI=13.8-17.1), respectively. Over the 24 yr incidence rates significantly increased by 8.5% for boys and 3.0% for girls. The highest increase of incidence rate was in the 5-9 age group. Discussion: The results obtained are in line with data from other studies showing that the incidence of T1DM has been increasing in almost all populations worldwide. ©2013, Editrice Kurtis.ChildrenEpidemiologyIncidenceRetrospective studyType 1 diabetes