Aliberti, Stefano (9247687000)Stefano (9247687000)AlibertiCook, Grayden S. (57326966700)Grayden S. (57326966700)CookBabu, Bettina L. (57195676280)Bettina L. (57195676280)BabuReyes, Luis F. (56660395500)Luis F. (56660395500)ReyesRodriguez, Alejandro H. (57221001871)Alejandro H. (57221001871)RodriguezSanz, Francisco (23095666000)Francisco (23095666000)SanzSoni, Nilam J. (55821625800)Nilam J. (55821625800)SoniAnzueto, Antonio (7005579878)Antonio (7005579878)AnzuetoFaverio, Paola (55581077200)Paola (55581077200)FaverioSadud, Ricardo Franco (57210147174)Ricardo Franco (57210147174)SadudMuhammad, Irfan (57210147993)Irfan (57210147993)MuhammadPrat, Cristina (57218192587)Cristina (57218192587)PratVendrell, Ester (55862900900)Ester (55862900900)VendrellNeves, Joao (57225332026)Joao (57225332026)NevesKaimakamis, Evangelos (20433719100)Evangelos (20433719100)KaimakamisFeneley, Andrew (57204522106)Andrew (57204522106)FeneleySwarnakar, Rajesh (55670269600)Rajesh (55670269600)SwarnakarFranzetti, Fabio (7004296673)Fabio (7004296673)FranzettiCarugati, Manuela (54782357900)Manuela (54782357900)CarugatiMorosi, Manuela (56028582100)Manuela (56028582100)MorosiMonge, Elisa (56543115100)Elisa (56543115100)MongeRestrepo, Marcos I. (7003493777)Marcos I. (7003493777)RestrepoAruj, Patricia Karina (22952662200)Patricia Karina (22952662200)ArujAttorri, Silvia (21638513500)Silvia (21638513500)AttorriBarimboim, Enrique (57204520842)Enrique (57204520842)BarimboimCaeiro, Juan Pablo (7003443410)Juan Pablo (7003443410)CaeiroGarzón, María I. (56600084800)María I. (56600084800)GarzónCambursano, Victor Hugo (35361690200)Victor Hugo (35361690200)CambursanoCeccato, Adrian (56349658400)Adrian (56349658400)CeccatoChertcoff, Julio (23472076800)Julio (23472076800)ChertcoffLascar, Florencia (57204934654)Florencia (57204934654)LascarDi Tulio, Fernando (57204929210)Fernando (57204929210)Di TulioDíaz, Ariel Cordon (57214115292)Ariel Cordon (57214115292)Díazde Vedia, Lautaro (16306426400)Lautaro (16306426400)de VediaGanaha, Maria Cristina (26322474600)Maria Cristina (26322474600)GanahaLambert, Sandra (57204521531)Sandra (57204521531)LambertLopardo, Gustavo (55890873500)Gustavo (55890873500)LopardoLuna, Carlos M. (57214546627)Carlos M. (57214546627)LunaMalberti, Alessio Gerardo (57204518948)Alessio Gerardo (57204518948)MalbertiMorcillo, Nora (55961163300)Nora (55961163300)MorcilloTartara, Silvina (57202535709)Silvina (57202535709)TartaraPensotti, Claudia (6508085918)Claudia (6508085918)PensottiPereyra, Betiana (35362535000)Betiana (35362535000)PereyraScapellato, Pablo Gustavo (7801596400)Pablo Gustavo (7801596400)ScapellatoStagnaro, Juan Pablo (57200195733)Juan Pablo (57200195733)StagnaroShah, Sonali (58809915100)Sonali (58809915100)ShahLötsch, Felix (55927273600)Felix (55927273600)LötschThalhammer, Florian (7007056281)Florian (7007056281)ThalhammerAnseeuw, Kurt (24390776800)Kurt (24390776800)AnseeuwFrancois, Camille A. (57204518580)Camille A. (57204518580)FrancoisVan Braeckel, Eva (8265309200)Eva (8265309200)Van BraeckelVincent, Jean Louis (7403122266)Jean Louis (7403122266)VincentDjimon, Marcel Zannou (57204521735)Marcel Zannou (57204521735)DjimonBashi, Jules (35298395600)Jules (35298395600)BashiDodo, Roger (57204424954)Roger (57204424954)DodoNouér, Simone Aranha (13008370100)Simone Aranha (13008370100)NouérChipev, Peter (57204518750)Peter (57204518750)ChipevEncheva, Milena (56672875300)Milena (56672875300)EnchevaMiteva, Darina (57204522014)Darina (57204522014)MitevaPetkova, Diana (57204520945)Diana (57204520945)PetkovaBalkissou, Adamou Dodo (55482682700)Adamou Dodo (55482682700)BalkissouYone, Eric Walter Pefura (54885262500)Eric Walter Pefura (54885262500)YoneNgahane, Bertrand Hugo Mbatchou (36057023600)Bertrand Hugo Mbatchou (36057023600)NgahaneShen, Ning (15133087500)Ning (15133087500)ShenXu, Jin-Fu (14119255300)Jin-Fu (14119255300)XuRico, Carlos Andres Bustamante (57210378774)Carlos Andres Bustamante (57210378774)RicoBuitrago, Ricardo (56800374700)Ricardo (56800374700)BuitragoPaternina, Fernando Jose Pereira (57210373698)Fernando Jose Pereira (57210373698)PaterninaNtumba, Jean-Marie Kayembe (57936122200)Jean-Marie Kayembe (57936122200)NtumbaCarevic, Vesna Vladic (57204930149)Vesna Vladic (57204930149)CarevicJakopovic, Marko (8679226900)Marko (8679226900)JakopovicJankovic, Mateja (16230215100)Mateja (16230215100)JankovicMatkovic, Zinka (54967977900)Zinka (54967977900)MatkovicMitrecic, Ivan (36195307900)Ivan (36195307900)MitrecicJacobsson, Marie-Laure Bouchy (55791414100)Marie-Laure Bouchy (55791414100)JacobssonChristensen, Anette Bro (57210376436)Anette Bro (57210376436)ChristensenBødtger, Uffe Christian Heitmann (56114002100)Uffe Christian Heitmann (56114002100)BødtgerMeyer, Christian Niels (57199135590)Christian Niels (57199135590)MeyerJensen, Andreas Vestergaard (36142903900)Andreas Vestergaard (36142903900)JensenBaunbæk-Knudsen, Gertrud (57188686056)Gertrud (57188686056)Baunbæk-KnudsenPetersen, Pelle Trier (57192107971)Pelle Trier (57192107971)PetersenAndersen, Stine (57192096163)Stine (57192096163)AndersenEl-Wahhab, Ibrahim El-Said Abd (57215617250)Ibrahim El-Said Abd (57215617250)El-WahhabMorsy, Nesreen Elsayed (57192394309)Nesreen Elsayed (57192394309)MorsyShafiek, Hanaa (56020613500)Hanaa (56020613500)ShafiekSobh, Eman (56728597500)Eman (56728597500)SobhAbdulsemed, Kedir Abdella (57204522386)Kedir Abdella (57204522386)AbdulsemedBertrand, Fabrice (57224654542)Fabrice (57224654542)BertrandBrun-Buisson, Christian (7101618837)Christian (7101618837)Brun-Buissonde Montmollin, Etienne (35760884500)Etienne (35760884500)de MontmollinFartoukh, Muriel (8399930300)Muriel (8399930300)FartoukhMessika, Jonathan (51864055000)Jonathan (51864055000)MessikaTattevin, Pierre (7003361868)Pierre (7003361868)TattevinKhoury, Abdo (24587703400)Abdo (24587703400)KhouryEbruke, Bernard (39660950000)Bernard (39660950000)EbrukeDreher, Michael (8712437500)Michael (8712437500)DreherKolditz, Martin (57220386054)Martin (57220386054)KolditzMeisinger, Matthias (57204522084)Matthias (57204522084)MeisingerPletz, Mathias W. 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(57204520753)José F. (57204520753)VillegasMedenica, Milic (7006004912)Milic (7006004912)Medenicavan de Garde, E.M.W. (9740982100)E.M.W. (9740982100)van de GardeMihsra, Deebya Raj (57210368833)Deebya Raj (57210368833)MihsraShrestha, Poojan (55777126900)Poojan (55777126900)ShresthaRidgeon, Elliott (56644864700)Elliott (56644864700)RidgeonAwokola, Babatunde Ishola (56467991500)Babatunde Ishola (56467991500)AwokolaNwankwo, Ogonna N.O. (56467943600)Ogonna N.O. (56467943600)NwankwoOlufunlola, Adefuye Bolanle (57204519493)Adefuye Bolanle (57204519493)OlufunlolaOlumide, Segaolu (57204522163)Segaolu (57204522163)OlumideUkwaja, Kingsley N. (57202824584)Kingsley N. (57202824584)UkwajaIrfan, Muhammad (57221471833)Muhammad (57221471833)IrfanMinarowski, Lukasz (16043240300)Lukasz (16043240300)MinarowskiSzymon, Skoczynski (57204518463)Skoczynski (57204518463)SzymonFroes, Felipe (7102530887)Felipe (7102530887)FroesLeuschner, Pedro (35364756800)Pedro (35364756800)LeuschnerMeireles, Mariana (57194410458)Mariana (57194410458)MeirelesFerrão, Cláudia (55899659000)Cláudia (55899659000)FerrãoRavara, Sofia B. (53164833700)Sofia B. (53164833700)RavaraBrocovschii, Victoria (55151579200)Victoria (55151579200)BrocovschiiIon, Chesov (57204521358)Chesov (57204521358)IonRusu, Doina (59069577000)Doina (59069577000)RusuToma, Cristina (57204521114)Cristina (57204521114)TomaChirita, Daniela (57204519779)Daniela (57204519779)ChiritaDorobat, Carmen Mihaela (6506162651)Carmen Mihaela (6506162651)DorobatBirkun, Alexei (7003748587)Alexei (7003748587)BirkunKaluzhenina, Anna (57193896435)Anna (57193896435)KaluzheninaAlmotairi, Abdullah (57188964531)Abdullah (57188964531)AlmotairiBukhary, Zakeya Abdulbaqi Ali (25642505900)Zakeya Abdulbaqi Ali (25642505900)BukharyEdathodu, Jameela (24176898800)Jameela (24176898800)EdathoduFathy, Amal (57192604855)Amal (57192604855)FathyEnani, Abdullah Mushira Abdulaziz (57210372813)Abdullah Mushira Abdulaziz (57210372813)EnaniMohamed, Nazik Eltayeb (57204933405)Nazik Eltayeb (57204933405)MohamedMemon, Jawed Ulhadi (57204931519)Jawed Ulhadi (57204931519)MemonBella, Abdelhaleem (37096590600)Abdelhaleem (37096590600)BellaBogdanovic, Nada (57210675124)Nada (57210675124)BogdanovicMilenkovic, Branislava (23005307400)Branislava (23005307400)MilenkovicPesut, Dragica (23101047600)Dragica (23101047600)PesutBorderìas, Luis (16168865800)Luis (16168865800)BorderìasGarcia, Noel Manuel Bordon (57210377573)Noel Manuel Bordon (57210377573)GarciaAlarcón, Hugo Cabello (57210984238)Hugo Cabello (57210984238)AlarcónCilloniz, Catia (36058487300)Catia (36058487300)CillonizTorres, Antoni (57205521091)Antoni (57205521091)TorresDiaz-Brito, Vicens (22953111800)Vicens (22953111800)Diaz-BritoCasas, Xavier (56631063500)Xavier (56631063500)CasasGonzález, Alicia Encabo (57210372602)Alicia Encabo (57210372602)GonzálezFernández-Almira, Maria Luisa (56586004200)Maria Luisa (56586004200)Fernández-AlmiraGallego, Miguel (55382766400)Miguel (55382766400)GallegoGaspar-García, Inmaculada (50461373300)Inmaculada (50461373300)Gaspar-GarcíaDel Castillo, Juan González (15063930000)Juan González (15063930000)Del CastilloVictoria, Patricia Javaloyes (57204930374)Patricia Javaloyes (57204930374)VictoriaMartínez, Elena Laserna (58587572600)Elena Laserna (58587572600)Martínezde Molina, Rosa Malo (24281230700)Rosa Malo (24281230700)de MolinaMarcos, Pedro J. (36573662800)Pedro J. (36573662800)MarcosMenéndez, Rosario (7102205716)Rosario (7102205716)MenéndezPando-Sandoval, Ana (55632666100)Ana (55632666100)Pando-SandovalAymerich, Cristina Prat (57204930201)Cristina Prat (57204930201)Aymerichde la Torre, Alicia Lacoma (57204930101)Alicia Lacoma (57204930101)de la TorreGarcía-Olivé, Ignasi (24176515900)Ignasi (24176515900)García-OlivéRello, Jordi (7102682070)Jordi (7102682070)RelloMoyano, Silvia (57204929008)Silvia (57204929008)MoyanoSibila, Oriol (8761639900)Oriol (8761639900)SibilaRodrigo-Troyano, Ana (56403368100)Ana (56403368100)Rodrigo-TroyanoSolé-Violán, Jordi (24391710100)Jordi (24391710100)Solé-ViolánUranga, Ane (55389666700)Ane (55389666700)Urangavan Boven, Job FM (53464198500)Job FM (53464198500)van BovenTorra, Ester Vendrell (57204933704)Ester Vendrell (57204933704)TorraPujol, Jordi Almirall (57198048750)Jordi Almirall (57198048750)PujolFeldman, Charles (7102504169)Charles (7102504169)FeldmanYum, Ho Kee (7004129428)Ho Kee (7004129428)YumFiogbe, Arnauld Attannon (57439244200)Arnauld Attannon (57439244200)FiogbeYangui, Ferdaous (56534205700)Ferdaous (56534205700)YanguiBilaceroglu, Semra (6603575876)Semra (6603575876)BilacerogluDalar, Levent (23033678300)Levent (23033678300)DalarYilmaz, Ufuk (57204516382)Ufuk (57204516382)YilmazBogomolov, Artemii (57218175167)Artemii (57218175167)BogomolovElahi, Naheed (57192166102)Naheed (57192166102)ElahiDhasmana, Devesh J. (18433352600)Devesh J. (18433352600)DhasmanaIons, Rhiannon (57204322388)Rhiannon (57204322388)IonsSkeemer, Julie (57204928064)Julie (57204928064)SkeemerWoltmann, Gerrit (8742371300)Gerrit (8742371300)WoltmannHancock, Carole (56079465800)Carole (56079465800)HancockHill, Adam T. (15041954900)Adam T. (15041954900)HillRudran, Banu (57202010897)Banu (57202010897)RudranRuiz-Buitrago, Silvia (57204516813)Silvia (57204516813)Ruiz-BuitragoCampbell, Marion (57193831661)Marion (57193831661)CampbellWhitaker, Paul (26634614800)Paul (26634614800)WhitakerYouzguin, Alexander (15059718100)Alexander (15059718100)YouzguinSinganayagam, Anika (47062101800)Anika (47062101800)SinganayagamAllen, Karen S. (59860445800)Karen S. (59860445800)AllenBrito, Veronica (6701599748)Veronica (6701599748)BritoDietz, Jessica (57204521217)Jessica (57204521217)DietzDysart, Claire E. (57204518726)Claire E. (57204518726)DysartKellie, Susan M. (37032726000)Susan M. (37032726000)KellieFranco-Sadud, Ricardo A. (35421934400)Ricardo A. (35421934400)Franco-SadudMeier, Garnet (57204520682)Garnet (57204520682)MeierGaga, Mina (34770698800)Mina (34770698800)GagaHolland, Thomas L. (35115075500)Thomas L. (35115075500)HollandBergin, Stephen P. (57217318521)Stephen P. (57217318521)BerginKheir, Fayez (36015464500)Fayez (36015464500)KheirLandmeier, Mark (57197821708)Mark (57197821708)LandmeierLois, Manuel (6602988699)Manuel (6602988699)LoisNair, Girish B. (37057878000)Girish B. (37057878000)NairPatel, Hemali (59822857800)Hemali (59822857800)PatelReyes, Katherine (26658662900)Katherine (26658662900)ReyesRodriguez-Cintron, William (6603463170)William (6603463170)Rodriguez-CintronSaito, Shigeki (56844198000)Shigeki (56844198000)SaitoNoda, Julio (57191978039)Julio (57191978039)NodaHinojosa, Cecilia I. (55918716800)Cecilia I. (55918716800)HinojosaLevine, Stephanie M. (21035079800)Stephanie M. (21035079800)LevineAngel, Luis F. (7003965832)Luis F. (7003965832)AngelWhitlow, K. Scott (57204934867)K. Scott (57204934867)WhitlowHipskind, John (6603397830)John (6603397830)HipskindSukhija, Kunal (57204521106)Kunal (57204521106)SukhijaTotten, Vicken (57204579345)Vicken (57204579345)TottenWunderink, Richard G. (57668575800)Richard G. (57668575800)WunderinkShah, Ray D. (57204517917)Ray D. (57204517917)ShahMateyo, Kondwelani John (56641736800)Kondwelani John (56641736800)MateyoNoriega, Lorena (58102647400)Lorena (58102647400)NoriegaAlvarado, Ezequiel (57204934449)Ezequiel (57204934449)AlvaradoAman, Mohamed (57204934258)Mohamed (57204934258)AmanLabra, Lucía (57204932226)Lucía (57204932226)Labra2025-06-122025-06-122019https://doi.org/10.1016/j.jinf.2019.07.004https://www.scopus.com/inward/record.uri?eid=2-s2.0-85069669834&doi=10.1016%2fj.jinf.2019.07.004&partnerID=40&md5=248510cb0e91f0103621d76777c8f5d8https://remedy.med.bg.ac.rs/handle/123456789/5355Objective: Streptococcus pneumoniae is the most frequent bacterial pathogen isolated in subjects with Community-acquired pneumonia (CAP) worldwide. Limited data are available regarding the current global burden and risk factors associated with drug-resistant Streptococcus pneumoniae (DRSP) in CAP subjects. We assessed the multinational prevalence and risk factors for DRSP-CAP in a multinational point-prevalence study. Design: The prevalence of DRSP-CAP was assessed by identification of DRSP in blood or respiratory samples among adults hospitalized with CAP in 54 countries. Prevalence and risk factors were compared among subjects that had microbiological testing and antibiotic susceptibility data. Multivariate logistic regressions were used to identify risk factors independently associated with DRSP-CAP. Results: 3,193 subjects were included in the study. The global prevalence of DRSP-CAP was 1.3% and continental prevalence rates were 7.0% in Africa, 1.2% in Asia, and 1.0% in South America, Europe, and North America, respectively. Macrolide resistance was most frequently identified in subjects with DRSP-CAP (0.6%) followed by penicillin resistance (0.5%). Subjects in Africa were more likely to have DRSP-CAP (OR: 7.6; 95%CI: 3.34-15.35, p<0.001) when compared to centres representing other continents. Conclusions: This multinational point-prevalence study found a low global prevalence of DRSP-CAP that may impact guideline development and antimicrobial policies. © 2019Global burden of diseaseMicrobial drug resistantPneumococcal infectionPneumonia